Pyrroles and other heterocycles as inhibitors of p38 kinase.
Тип публикации: Journal Article
Дата публикации: 1998-10-01
scimago Q2
wos Q2
БС2
SJR: 0.472
CiteScore: 5.1
Impact factor: 2.2
ISSN: 0960894X, 14643405
PubMed ID:
9873604
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Краткое описание
Investigation of furans, pyrroles and pyrazolones identified 3-pyridyl-2,5-diaryl-pyrroles as potent, orally bioavailable inhibitors of p38 kinase. 3-(4-pyridyl-2-(4-fluoro-phenyl)-5-(4-methylsulfinylphenyl)-pyrrol e (L-167307) reduces secondary paw swelling in the rat adjuvant arthritis model: ID50 = 7.4 mg/kg/b.i.d.
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107
Всего цитирований:
107
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ГОСТ |
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BibTex |
MLA
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ГОСТ
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de Laszlo S. E. et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. // Bioorganic and Medicinal Chemistry Letters. 1998. Vol. 8. No. 19. pp. 2689-2694.
ГОСТ со всеми авторами (до 50)
Скопировать
de Laszlo S. E., Visco D., Agarwal L., Chang L., Chin J., Croft G. F., Forsyth A., Fletcher D. J., Frantz B., Hacker C., HANLON W., Harper C., Kostura M., Li B., Luell S., MacCOSS M., Mantlo N., O'Neill E. A., Orevillo C., Pang M., Parsons J., Rolando A., Sahly Y., Sidler K., Widmer W. R., O'Keefe S. J. Pyrroles and other heterocycles as inhibitors of p38 kinase. // Bioorganic and Medicinal Chemistry Letters. 1998. Vol. 8. No. 19. pp. 2689-2694.
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RIS
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TY - JOUR
DO - 10.1016/S0960-894X(98)00495-8
UR - https://doi.org/10.1016/S0960-894X(98)00495-8
TI - Pyrroles and other heterocycles as inhibitors of p38 kinase.
T2 - Bioorganic and Medicinal Chemistry Letters
AU - de Laszlo, Stephen E
AU - Visco, Denise
AU - Agarwal, Lily
AU - Chang, Linda
AU - Chin, Jayne
AU - Croft, G. F.
AU - Forsyth, Amy
AU - Fletcher, Daniel J.
AU - Frantz, Betsy
AU - Hacker, Candice
AU - HANLON, W.
AU - Harper, Coral
AU - Kostura, Matthew
AU - Li, Bing
AU - Luell, Sylvie
AU - MacCOSS, MALCOLM
AU - Mantlo, Nathan
AU - O'Neill, Edward A.
AU - Orevillo, Chad
AU - Pang, Margaret
AU - Parsons, Janey
AU - Rolando, Anna
AU - Sahly, Yousif
AU - Sidler, Kelley
AU - Widmer, W Rick
AU - O'Keefe, Stephen J.
PY - 1998
DA - 1998/10/01
PB - Elsevier
SP - 2689-2694
IS - 19
VL - 8
PMID - 9873604
SN - 0960-894X
SN - 1464-3405
ER -
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BibTex (до 50 авторов)
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@article{1998_de Laszlo,
author = {Stephen E de Laszlo and Denise Visco and Lily Agarwal and Linda Chang and Jayne Chin and G. F. Croft and Amy Forsyth and Daniel J. Fletcher and Betsy Frantz and Candice Hacker and W. HANLON and Coral Harper and Matthew Kostura and Bing Li and Sylvie Luell and MALCOLM MacCOSS and Nathan Mantlo and Edward A. O'Neill and Chad Orevillo and Margaret Pang and Janey Parsons and Anna Rolando and Yousif Sahly and Kelley Sidler and W Rick Widmer and Stephen J. O'Keefe},
title = {Pyrroles and other heterocycles as inhibitors of p38 kinase.},
journal = {Bioorganic and Medicinal Chemistry Letters},
year = {1998},
volume = {8},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/S0960-894X(98)00495-8},
number = {19},
pages = {2689--2694},
doi = {10.1016/S0960-894X(98)00495-8}
}
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MLA
Скопировать
de Laszlo, Stephen E., et al. “Pyrroles and other heterocycles as inhibitors of p38 kinase..” Bioorganic and Medicinal Chemistry Letters, vol. 8, no. 19, Oct. 1998, pp. 2689-2694. https://doi.org/10.1016/S0960-894X(98)00495-8.