Methods in Enzymology, pages 403-433
Electronic biosensors based on EGOFETs
2
CSGI (Centre for Colloid and Surface Science), Unit of Bari, Bari, Italy
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Publication type: Book Chapter
Publication date: 2020-07-24
Journal:
Methods in Enzymology
Quartile SCImago
— Quartile WOS
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Impact factor: —
ISSN: 00766879, 15577988
Abstract
There is an increasing interest for low cost, ultrasensitive, time saving yet reliable, point-of-care bioelectronic sensors. Electrolyte gated organic field effect transistors (EGOFETs) are proven compelling transducers for various sensing applications, offering direct electronic, label-free transduction of bio-recognition events along with miniaturization, fast data handling and processing. Given that field effect transistors act as intrinsically signal amplifiers, even a small change of a chemical or biological quantity may significantly alter the output electronic signal. In EGOFETs selectivity can be guaranteed by the immobilization of bioreceptors able to bind specifically a target analyte. The layer of receptors can be linked to one of the electronic active interfaces of the transistor, and the interactions with a target molecule affect the electronic properties of the device. The present chapter discusses main aspects of EGOFETs transducers along with detailed examples of how to tailor the device interfaces with desired functionality. The development of an “electronic tongue” based on an EGOFET device coupled to odorant binding proteins (OBPs) for enantiomers differentiation is presented.
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TY - GENERIC
DO - 10.1016/bs.mie.2020.07.003
UR - https://doi.org/10.1016/bs.mie.2020.07.003
TI - Electronic biosensors based on EGOFETs
T2 - Methods in Enzymology
AU - Mulla, Mohammad Y.
AU - Torsi, L.
AU - Manoli, Kyriaki
PY - 2020
DA - 2020/07/24 00:00:00
PB - Elsevier
SP - 403-433
SN - 0076-6879
SN - 1557-7988
ER -
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@incollection{2020_Mulla,
author = {Mohammad Y. Mulla and L. Torsi and Kyriaki Manoli},
title = {Electronic biosensors based on EGOFETs},
publisher = {Elsevier},
year = {2020},
pages = {403--433},
month = {jul}
}