Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems
Yu-Jung Lin
1
,
Fwu-Long Mi
2
,
PO-YEN LIN
1
,
Yang Bao Miao
1
,
Tringyo Huang
1
,
Kuan-Hung Chen
1
,
Chiung-Yu Chen
3
,
Yen Chang
4
,
Hsing W. Sung
1
3
Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Miaoli, Taiwan (ROC)
|
Publication type: Journal Article
Publication date: 2019-01-01
scimago Q1
wos Q1
SJR: 3.721
CiteScore: 36.0
Impact factor: 17.6
ISSN: 0169409X, 18728294
PubMed ID:
30529306
Pharmaceutical Science
Abstract
The encapsulation of insulin in micro- or nanodelivery systems may eliminate the need for frequent subcutaneous injections, improving the quality of life of diabetic patients. Formulations for oral, intranasal, pulmonary, subcutaneous, and transdermal administration have been developed. The use of stimuli-responsive polymeric carriers that can release the encapsulated drug in response to changes of the environmental stimuli or external activation enables the design of less invasive or non-invasive systems for smart insulin delivery from depots in the body. This article will look at strategies for the development of responsive delivery systems and the future meeting of the demands of new modes of insulin delivery.
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Metrics
38
Total citations:
38
Citations from 2024:
10
(26.32%)
Cite this
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RIS |
BibTex
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GOST
Copy
Lin Y. et al. Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems // Advanced Drug Delivery Reviews. 2019. Vol. 139. pp. 71-82.
GOST all authors (up to 50)
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Lin Y., Mi F., LIN P., Miao Y. B., Huang T., Chen K., Chen C., Chang Y., Sung H. W. Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems // Advanced Drug Delivery Reviews. 2019. Vol. 139. pp. 71-82.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.addr.2018.12.001
UR - https://doi.org/10.1016/j.addr.2018.12.001
TI - Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems
T2 - Advanced Drug Delivery Reviews
AU - Lin, Yu-Jung
AU - Mi, Fwu-Long
AU - LIN, PO-YEN
AU - Miao, Yang Bao
AU - Huang, Tringyo
AU - Chen, Kuan-Hung
AU - Chen, Chiung-Yu
AU - Chang, Yen
AU - Sung, Hsing W.
PY - 2019
DA - 2019/01/01
PB - Elsevier
SP - 71-82
VL - 139
PMID - 30529306
SN - 0169-409X
SN - 1872-8294
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Lin,
author = {Yu-Jung Lin and Fwu-Long Mi and PO-YEN LIN and Yang Bao Miao and Tringyo Huang and Kuan-Hung Chen and Chiung-Yu Chen and Yen Chang and Hsing W. Sung},
title = {Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems},
journal = {Advanced Drug Delivery Reviews},
year = {2019},
volume = {139},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.addr.2018.12.001},
pages = {71--82},
doi = {10.1016/j.addr.2018.12.001}
}