Open Access

Biomedicine and Pharmacotherapy, volume 143, pages 112158

A mini-review on the impact of COVID 19 on vital organs

Muhammad Raza Shah ¹

Aini Simon Sumeh ²

Muhammad Ali Sheraz ³

Muthu Subash Kavitha ⁴

BALU ALAGAR VENMATHI MARAN ⁵

KENNETH FRANCIS RODRIGUES ⁶

Hide authors affiliations Show authors affiliations: 6 affiliations

Borneo Marine Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia. Electronic address: dawoodshah@ums.edu.my. |

Penampang Health Clinic, Kampung Tuavon, 89500 Penampang, Sabah, Malaysia. |

Arbutus Biopharma Inc, 701 Veterans Circle, Warminster, PA 18974, USA. |

⁴

School of Information and Data Sciences, Nagasaki University, Bunkyo-machi 1-14, Nagasaki 852-8521, Japan. Electronic address: kavitha@nagasaki-u.ac.jp. |

⁵

Borneo Marine Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia. Electronic address: bavmaran@ums.edu.my. |

⁶

Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia. Electronic address: kennethr@ums.edu.my. |

Publication type: Journal Article

Publication date: 2021-11-01

Elsevier

Journal: Biomedicine and Pharmacotherapy

Quartile SCImago

Quartile WOS

Impact factor: 7.5

ISSN: 07533322

DOI: 10.1016/j.biopha.2021.112158

Copy DOI

General Medicine

Pharmacology

Abstract

COVID-19 (Corona Virus Disease-2019) is an infectious disease caused by a novel coronavirus, known as the acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is a highly contagious disease that has already affected more than 220 countries globally, infecting more than 212 million people and resulting in the death of over 4.4 million people. This review aims to highlight the pertinent documentary evidence upon the adverse effects of the SARS-CoV-2 infection on several vital human organs. SARS-CoV-2 primarily targets the lung tissue by causing diffuse alveolar damage and may result in Acute Respiratory Distress Syndrome (ARDS). SARS-CoV-2 infects the cell via cell surface receptor, angiotensin-converting enzyme 2 (ACE2). Besides lungs, SARS-CoV-2 critically damage tissues in other vital human organs such as the heart, kidney, liver, brain, and gastrointestinal tract. The effect on the heart includes muscle dysfunction (acute or protracted heart failure), myocarditis, and cell necrosis. Within hepatic tissue, it alters serum aminotransferase, total bilirubin, and gamma-glutamyl transferase levels. It contributes to acute kidney injury (AKI). Localized infection of the brain can lead to loss or attenuation of olfaction, muscular pain, headaches, encephalopathy, dizziness, dysgeusia, psychomotor disorders, and stroke; while the gastrointestinal symptoms include the disruption of the normal intestinal mucosa, leading to diarrhea and abdominal pain. This review encompassed a topical streak of systemic malfunctions caused by the SARS-CoV-2 infection. As the pandemic is still in progress, more studies will enrich our understanding and analysis of this disease.

By date By citations

Top-30

Citations by journals

	1 2 3
Journal of Clinical Medicine	Journal of Clinical Medicine, 3, 8.57% Journal of Clinical Medicine 3 publications, 8.57%
Biomolecules	Biomolecules, 2, 5.71% Biomolecules 2 publications, 5.71%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 2, 5.71% International Journal of Molecular Sciences 2 publications, 5.71%
International Journal of Environmental Research and Public Health	International Journal of Environmental Research and Public Health, 2, 5.71% International Journal of Environmental Research and Public Health 2 publications, 5.71%
Virology	Virology, 1, 2.86% Virology 1 publication, 2.86%
Healthcare	Healthcare, 1, 2.86% Healthcare 1 publication, 2.86%
Frontiers in Medicine	Frontiers in Medicine, 1, 2.86% Frontiers in Medicine 1 publication, 2.86%
Inflammation Research	Inflammation Research, 1, 2.86% Inflammation Research 1 publication, 2.86%
Bulletin of Experimental Biology and Medicine	Bulletin of Experimental Biology and Medicine, 1, 2.86% Bulletin of Experimental Biology and Medicine 1 publication, 2.86%
Kardiologicheskii vestnik	Kardiologicheskii vestnik, 1, 2.86% Kardiologicheskii vestnik 1 publication, 2.86%
Revista da Sociedade Brasileira de Medicina Tropical	Revista da Sociedade Brasileira de Medicina Tropical, 1, 2.86% Revista da Sociedade Brasileira de Medicina Tropical 1 publication, 2.86%
Journal of the American Heart Association	Journal of the American Heart Association, 1, 2.86% Journal of the American Heart Association 1 publication, 2.86%
Electrochimica Acta	Electrochimica Acta, 1, 2.86% Electrochimica Acta 1 publication, 2.86%
Frontiers in Immunology	Frontiers in Immunology, 1, 2.86% Frontiers in Immunology 1 publication, 2.86%
European Journal of Human Genetics	European Journal of Human Genetics, 1, 2.86% European Journal of Human Genetics 1 publication, 2.86%
Biomedicines	Biomedicines, 1, 2.86% Biomedicines 1 publication, 2.86%
Vaccines	Vaccines, 1, 2.86% Vaccines 1 publication, 2.86%
Health Science Reports	Health Science Reports, 1, 2.86% Health Science Reports 1 publication, 2.86%
IEEE Access	IEEE Access, 1, 2.86% IEEE Access 1 publication, 2.86%
QJM - Monthly Journal of the Association of Physicians	QJM - Monthly Journal of the Association of Physicians, 1, 2.86% QJM - Monthly Journal of the Association of Physicians 1 publication, 2.86%
International journal of nursing knowledge	International journal of nursing knowledge, 1, 2.86% International journal of nursing knowledge 1 publication, 2.86%
Infectious Disease Reports	Infectious Disease Reports, 1, 2.86% Infectious Disease Reports 1 publication, 2.86%
Diagnostics	Diagnostics, 1, 2.86% Diagnostics 1 publication, 2.86%
Russian Chemical Reviews	Russian Chemical Reviews, 1, 2.86% Russian Chemical Reviews 1 publication, 2.86%
Inflammopharmacology	Inflammopharmacology, 1, 2.86% Inflammopharmacology 1 publication, 2.86%
Journal of Nutrition, Health and Aging	Journal of Nutrition, Health and Aging, 1, 2.86% Journal of Nutrition, Health and Aging 1 publication, 2.86%
	1 2 3

Citations by publishers

	2 4 6 8 10 12 14
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 14, 40% Multidisciplinary Digital Publishing Institute (MDPI) 14 publications, 40%
Springer Nature	Springer Nature, 5, 14.29% Springer Nature 5 publications, 14.29%
Wiley	Wiley, 3, 8.57% Wiley 3 publications, 8.57%
Elsevier	Elsevier, 2, 5.71% Elsevier 2 publications, 5.71%
Frontiers Media S.A.	Frontiers Media S.A., 2, 5.71% Frontiers Media S.A. 2 publications, 5.71%
Cold Spring Harbor Laboratory	Cold Spring Harbor Laboratory, 2, 5.71% Cold Spring Harbor Laboratory 2 publications, 5.71%
Media Sphere Publishing Group	Media Sphere Publishing Group, 1, 2.86% Media Sphere Publishing Group 1 publication, 2.86%
Sociedade Brasileira de Medicina Tropical	Sociedade Brasileira de Medicina Tropical, 1, 2.86% Sociedade Brasileira de Medicina Tropical 1 publication, 2.86%
IEEE	IEEE, 1, 2.86% IEEE 1 publication, 2.86%
Oxford University Press	Oxford University Press, 1, 2.86% Oxford University Press 1 publication, 2.86%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii	Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii, 1, 2.86% Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii 1 publication, 2.86%
	2 4 6 8 10 12 14

We do not take into account publications without a DOI.
Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
Statistics recalculated weekly.

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Shah M. R. et al. A mini-review on the impact of COVID 19 on vital organs // Biomedicine and Pharmacotherapy. 2021. Vol. 143. p. 112158.

GOST all authors (up to 50) Copy

Shah M. R., Sumeh A. S., Sheraz M. A., Kavitha M. S., MARAN B. A. V., RODRIGUES K. F. A mini-review on the impact of COVID 19 on vital organs // Biomedicine and Pharmacotherapy. 2021. Vol. 143. p. 112158.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.biopha.2021.112158

UR - https://doi.org/10.1016/j.biopha.2021.112158

TI - A mini-review on the impact of COVID 19 on vital organs

T2 - Biomedicine and Pharmacotherapy

AU - Shah, Muhammad Raza

AU - Sumeh, Aini Simon

AU - Sheraz, Muhammad Ali

AU - Kavitha, Muthu Subash

AU - MARAN, BALU ALAGAR VENMATHI

AU - RODRIGUES, KENNETH FRANCIS

PY - 2021

DA - 2021/11/01 00:00:00

PB - Elsevier

SP - 112158

VL - 143

SN - 0753-3322

ER -

BibTex

Cite this

BibTex Copy

@article{2021_Shah,

author = {Muhammad Raza Shah and Aini Simon Sumeh and Muhammad Ali Sheraz and Muthu Subash Kavitha and BALU ALAGAR VENMATHI MARAN and KENNETH FRANCIS RODRIGUES},

title = {A mini-review on the impact of COVID 19 on vital organs},

journal = {Biomedicine and Pharmacotherapy},

year = {2021},

volume = {143},

publisher = {Elsevier},

month = {nov},

url = {https://doi.org/10.1016/j.biopha.2021.112158},

pages = {112158},

doi = {10.1016/j.biopha.2021.112158}

}

Found error?

Publisher

Elsevier

Journal

Biomedicine and Pharmacotherapy

Quartile SCImago

Quartile WOS

Impact factor

7.5

ISSN

07533322 (Print)