Biosensors and Bioelectronics, volume 237, pages 115450
Lab-made flexible third-generation fructose biosensors based on 0D-nanostructured transducers
Filippo Silveri
1
,
Davide Paolini
1
,
Flavio Della Pelle
1
,
Paolo Bollella
2
,
Annalisa Scroccarello
1
,
Yu Suzuki
3
,
Eole Fukawa
3
,
Keisei SOWA
3
,
Cinzia Di Franco
4
,
L. Torsi
2, 5
,
4
Publication type: Journal Article
Publication date: 2023-10-01
Journal:
Biosensors and Bioelectronics
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 12.6
ISSN: 09565663, 18734235
General Medicine
Biophysics
Electrochemistry
Biotechnology
Biomedical Engineering
Abstract
Herein, we report a scalable benchtop electrode fabrication method to produce highly sensitive and flexible third-generation fructose dehydrogenase amperometric biosensors based on water-dispersed 0D-nanomaterials. The electrochemical platform was fabricated via Stencil-Printing (StPE) and insulated via xurography. Carbon black (CB) and mesoporous carbon (MS) were employed as 0D-nanomaterials promoting an efficient direct electron transfer (DET) between fructose dehydrogenase (FDH) and the transducer. Both nanomaterials were prepared in water-phase via a sonochemical approach. The nano-StPE exhibited enhanced electrocatalytic currents compared to conventional commercial electrodes. The enzymatic sensors were exploited for the determination of D-fructose in model solutions and various food and biological samples. StPE-CB and StPE-MS integrated biosensors showed appreciable sensitivity (∼150 μA cm−2 mM−1) with μmolar limit of detection (0.35 and 0.16 μM, respectively) and extended linear range (2–500 and 1–250 μM, respectively); the selectivity of the biosensors, ensured by the low working overpotential (+0.15 V), has been also demonstrated. Good accuracy (recoveries between 95 and 116%) and reproducibility (RSD ≤8.6%) were achieved for honey and urine samples. The proposed approach because of manufacturing versatility and the electro-catalytic features of the water-nanostructured 0D-NMs opens new paths for affordable and customizable FDH-based bioelectronics.
Top-30
Citations by journals
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1
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Small
1 publication, 9.09%
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Chemistry of Materials
1 publication, 9.09%
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Journal Physics D: Applied Physics
1 publication, 9.09%
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ACS applied materials & interfaces
1 publication, 9.09%
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Russian Chemical Reviews
1 publication, 9.09%
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Measurement: Journal of the International Measurement Confederation
1 publication, 9.09%
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Denki Kagaku
1 publication, 9.09%
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Biosensors and Bioelectronics
1 publication, 9.09%
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Biosensors
1 publication, 9.09%
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Analytical and Bioanalytical Chemistry
1 publication, 9.09%
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Sensors and Actuators, B: Chemical
1 publication, 9.09%
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1
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Citations by publishers
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1
2
3
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Elsevier
3 publications, 27.27%
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American Chemical Society (ACS)
2 publications, 18.18%
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Wiley
1 publication, 9.09%
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IOP Publishing
1 publication, 9.09%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 9.09%
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The Electrochemical Society of Japan
1 publication, 9.09%
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 9.09%
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Springer Nature
1 publication, 9.09%
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1
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3
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Silveri F. et al. Lab-made flexible third-generation fructose biosensors based on 0D-nanostructured transducers // Biosensors and Bioelectronics. 2023. Vol. 237. p. 115450.
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Silveri F., Paolini D., Della Pelle F., Bollella P., Scroccarello A., Suzuki Yu., Fukawa E., SOWA K., Di Franco C., Torsi L., Compagnone D. Lab-made flexible third-generation fructose biosensors based on 0D-nanostructured transducers // Biosensors and Bioelectronics. 2023. Vol. 237. p. 115450.
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TY - JOUR
DO - 10.1016/j.bios.2023.115450
UR - https://doi.org/10.1016/j.bios.2023.115450
TI - Lab-made flexible third-generation fructose biosensors based on 0D-nanostructured transducers
T2 - Biosensors and Bioelectronics
AU - Silveri, Filippo
AU - Paolini, Davide
AU - Della Pelle, Flavio
AU - Bollella, Paolo
AU - Scroccarello, Annalisa
AU - Suzuki, Yu
AU - Fukawa, Eole
AU - SOWA, Keisei
AU - Di Franco, Cinzia
AU - Torsi, L.
AU - Compagnone, Dario
PY - 2023
DA - 2023/10/01 00:00:00
PB - Elsevier
SP - 115450
VL - 237
SN - 0956-5663
SN - 1873-4235
ER -
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@article{2023_Silveri,
author = {Filippo Silveri and Davide Paolini and Flavio Della Pelle and Paolo Bollella and Annalisa Scroccarello and Yu Suzuki and Eole Fukawa and Keisei SOWA and Cinzia Di Franco and L. Torsi and Dario Compagnone},
title = {Lab-made flexible third-generation fructose biosensors based on 0D-nanostructured transducers},
journal = {Biosensors and Bioelectronics},
year = {2023},
volume = {237},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/j.bios.2023.115450},
pages = {115450},
doi = {10.1016/j.bios.2023.115450}
}
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