Open Access
Biosensors and Bioelectronics: X, volume 10, pages 100126
Aptamer-drug conjugates: New probes for imaging and targeted therapy
Publication type: Journal Article
Publication date: 2022-05-01
Journal:
Biosensors and Bioelectronics: X
Quartile SCImago
Q1
Quartile WOS
—
Impact factor: —
ISSN: 25901370, 25901370
Biophysics
Electrochemistry
Biotechnology
Biomedical Engineering
Abstract
Since the discovery of aptamer, aptamer has become an exciting and promising diagnostic and therapeutic tool because of its excellent targeting selectivity, high potential affinity, simple modification, scalability, flexibility, low immunogenicity and a wide range of drug delivery platforms. Targeted therapy is the frontier research of modern medicine on countless clinical diseases. Aptamer is the focus of biological targeting research, especially tumor research. They not only have high clinical application potential in tumor targeted detection, but also have high application prospects in tumor therapy as targeted tumor drug carriers. In this review, we summarize the progress of aptamers in imaging technology and targeted therapy. We will focus on aptamer based targeted therapy, using aptamers as biotechnology tools and targeted therapeutic agents for targeted drug delivery. • Conjugate of Aptamer and drug has become one of the most hot research areas. • Targeted therapy is frontier research in modern medicine for countless clinical diseases. • The application of the aspects of G-Quadruplex's Aptamers binding therapy and modification respectively.
Top-30
Citations by journals
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1
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Archives of Pharmacal Research
1 publication, 20%
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ACS Omega
1 publication, 20%
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Journal of Drug Targeting
1 publication, 20%
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Russian Chemical Reviews
1 publication, 20%
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European Polymer Journal
1 publication, 20%
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1
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Citations by publishers
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1
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Pharmaceutical Society of Korea
1 publication, 20%
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American Chemical Society (ACS)
1 publication, 20%
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Taylor & Francis
1 publication, 20%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 20%
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Elsevier
1 publication, 20%
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1
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Liu P. et al. Aptamer-drug conjugates: New probes for imaging and targeted therapy // Biosensors and Bioelectronics: X. 2022. Vol. 10. p. 100126.
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Liu P., Ga L., Aodeng G., Wang Y., Ai J. Aptamer-drug conjugates: New probes for imaging and targeted therapy // Biosensors and Bioelectronics: X. 2022. Vol. 10. p. 100126.
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TY - JOUR
DO - 10.1016/j.biosx.2022.100126
UR - https://doi.org/10.1016/j.biosx.2022.100126
TI - Aptamer-drug conjugates: New probes for imaging and targeted therapy
T2 - Biosensors and Bioelectronics: X
AU - Liu, P
AU - Ga, L
AU - Aodeng, G
AU - Wang, Y
AU - Ai, J
PY - 2022
DA - 2022/05/01 00:00:00
PB - Elsevier
SP - 100126
VL - 10
SN - 2590-1370
SN - 2590-1370
ER -
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@article{2022,
author = {P Liu and L Ga and G Aodeng and Y Wang and J Ai},
title = {Aptamer-drug conjugates: New probes for imaging and targeted therapy},
journal = {Biosensors and Bioelectronics: X},
year = {2022},
volume = {10},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.biosx.2022.100126},
pages = {100126},
doi = {10.1016/j.biosx.2022.100126}
}