Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1
Тип публикации: Journal Article
Дата публикации: 2007-08-01
scimago Q2
wos Q1
БС1
SJR: 0.608
CiteScore: 6.7
Impact factor: 3
ISSN: 09680896, 14643391
PubMed ID:
17507232
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Краткое описание
A series of analogues of the potentially angiogenic inhibitor aeroplysinin-1 1 were synthesized and their in vitro antiangiogenic and cytotoxic activities evaluated. In the case of epoxy ketone 6 and azlactone 36 the relationship sprouting inhibition assay/cytotoxicity in BAE cells was enhanced by one order and two orders of magnitude, respectively, with respect to the reference. These results imply more specific antiangiogenic properties for the synthesized derivatives.
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ГОСТ
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Cordoba R. et al. Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1 // Bioorganic and Medicinal Chemistry. 2007. Vol. 15. No. 15. pp. 5300-5315.
ГОСТ со всеми авторами (до 50)
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Cordoba R., Tormo N. S., Medarde A. F., Plumet J. Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1 // Bioorganic and Medicinal Chemistry. 2007. Vol. 15. No. 15. pp. 5300-5315.
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RIS
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TY - JOUR
DO - 10.1016/j.bmc.2007.05.011
UR - https://doi.org/10.1016/j.bmc.2007.05.011
TI - Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1
T2 - Bioorganic and Medicinal Chemistry
AU - Cordoba, Ruben
AU - Tormo, Nélida Salvador
AU - Medarde, Antonio Fernández
AU - Plumet, Joaquín
PY - 2007
DA - 2007/08/01
PB - Elsevier
SP - 5300-5315
IS - 15
VL - 15
PMID - 17507232
SN - 0968-0896
SN - 1464-3391
ER -
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BibTex (до 50 авторов)
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@article{2007_Cordoba,
author = {Ruben Cordoba and Nélida Salvador Tormo and Antonio Fernández Medarde and Joaquín Plumet},
title = {Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1},
journal = {Bioorganic and Medicinal Chemistry},
year = {2007},
volume = {15},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.bmc.2007.05.011},
number = {15},
pages = {5300--5315},
doi = {10.1016/j.bmc.2007.05.011}
}
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MLA
Скопировать
Cordoba, Ruben, et al. “Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1.” Bioorganic and Medicinal Chemistry, vol. 15, no. 15, Aug. 2007, pp. 5300-5315. https://doi.org/10.1016/j.bmc.2007.05.011.