Bioorganic and Medicinal Chemistry, volume 25, issue 1, pages 91-99
Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation.
E.V. Shchegol’kov
1
,
I V Shchur
1
,
Ya. V. Burgart
1
,
V. I. Saloutin
1
,
A N Trefilova
2
,
G A Ljushina
2
,
S Yu Solodnikov
2
,
L.N. Markova
2
,
Vera V Maslova
2
,
O P Krasnykh
2
,
Publication type: Journal Article
Publication date: 2017-01-01
Journal:
Bioorganic and Medicinal Chemistry
Quartile SCImago
Q2
Quartile WOS
Q1
Impact factor: 3.5
ISSN: 09680896, 14643391
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
We have developed the convenient methods for synthesis of polyfluorosalicylic acids and their derivatives. For the first time the biological properties of polyfluorosalicylates were investigated in vitro (permeability through the biological membranes, COX-1 inhibitory action) and in vivo (anti-inflammatory, analgesic activities, acute toxicity). Molecular docking of polyfluorinated salicylates confirmed in vitro and in vivo experiments.
Top-30
Citations by journals
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2
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Polyhedron
2 publications, 11.76%
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Mendeleev Communications
2 publications, 11.76%
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ChemistrySelect
2 publications, 11.76%
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Medicinal Chemistry Research
1 publication, 5.88%
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Medicinal Chemistry
1 publication, 5.88%
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Journal of Chemical Sciences
1 publication, 5.88%
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DARU, Journal of Pharmaceutical Sciences
1 publication, 5.88%
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European Journal of Medicinal Chemistry
1 publication, 5.88%
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ChemMedChem
1 publication, 5.88%
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Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
1 publication, 5.88%
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European Journal of Organic Chemistry
1 publication, 5.88%
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Journal of Fluorine Chemistry
1 publication, 5.88%
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AIP Conference Proceedings
1 publication, 5.88%
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Russian Chemical Reviews
1 publication, 5.88%
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1
2
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Citations by publishers
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1
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3
4
5
6
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Elsevier
6 publications, 35.29%
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Wiley
4 publications, 23.53%
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Springer Nature
3 publications, 17.65%
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Bentham Science
1 publication, 5.88%
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Walter de Gruyter
1 publication, 5.88%
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American Institute of Physics (AIP)
1 publication, 5.88%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 5.88%
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Shchegol’kov E. et al. Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation. // Bioorganic and Medicinal Chemistry. 2017. Vol. 25. No. 1. pp. 91-99.
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Shchegol’kov E., Shchur I. V., Burgart Y. V., Saloutin V. I., Trefilova A. N., Ljushina G. A., Solodnikov S. Yu., Markova L., Maslova V. V., Krasnykh O. P., Borisevich S. S., Khursan S. L. Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation. // Bioorganic and Medicinal Chemistry. 2017. Vol. 25. No. 1. pp. 91-99.
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TY - JOUR
DO - 10.1016/j.bmc.2016.10.014
UR - https://doi.org/10.1016/j.bmc.2016.10.014
TI - Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation.
T2 - Bioorganic and Medicinal Chemistry
AU - Shchegol’kov, E.V.
AU - Shchur, I V
AU - Burgart, Ya. V.
AU - Saloutin, V. I.
AU - Trefilova, A N
AU - Ljushina, G A
AU - Solodnikov, S Yu
AU - Markova, L.N.
AU - Maslova, Vera V
AU - Krasnykh, O P
AU - Borisevich, Sophia S.
AU - Khursan, Sergey L.
PY - 2017
DA - 2017/01/01 00:00:00
PB - Elsevier
SP - 91-99
IS - 1
VL - 25
SN - 0968-0896
SN - 1464-3391
ER -
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@article{2017_Shchegol’kov,
author = {E.V. Shchegol’kov and I V Shchur and Ya. V. Burgart and V. I. Saloutin and A N Trefilova and G A Ljushina and S Yu Solodnikov and L.N. Markova and Vera V Maslova and O P Krasnykh and Sophia S. Borisevich and Sergey L. Khursan},
title = {Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation.},
journal = {Bioorganic and Medicinal Chemistry},
year = {2017},
volume = {25},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.bmc.2016.10.014},
number = {1},
pages = {91--99},
doi = {10.1016/j.bmc.2016.10.014}
}
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Shchegol’kov, E.V., et al. “Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation..” Bioorganic and Medicinal Chemistry, vol. 25, no. 1, Jan. 2017, pp. 91-99. https://doi.org/10.1016/j.bmc.2016.10.014.
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