Bioorganic and Medicinal Chemistry, volume 26, issue 10, pages 2850-2858

Advances in macrocyclic peptide-based antibiotics

Luther Anatol 1
Bisang Christian 1
Obrecht Daniel 1
1
 
Polyphor Ltd, Hegenheimermattweg 125, CH-4123 Allschwil, Switzerland.
Publication typeJournal Article
Publication date2018-06-01
Quartile SCImago
Q2
Quartile WOS
Q1
Impact factor3.5
ISSN09680896, 14643391
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
Macrocyclic peptide-based natural products have provided powerful new antibiotic drugs, drug candidates, and scaffolds for medicinal chemists as a source of inspiration to design novel antibiotics. While most of those natural products are active mainly against Gram-positive pathogens, novel macrocyclic peptide-based compounds have recently been described, which exhibit potent and specific activity against some of the most problematic Gram-negative ESKAPE pathogens. This mini-review gives an up-date on recent developments.

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GOST |
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GOST Copy
Luther A., Bisang C., Obrecht D. Advances in macrocyclic peptide-based antibiotics // Bioorganic and Medicinal Chemistry. 2018. Vol. 26. No. 10. pp. 2850-2858.
GOST all authors (up to 50) Copy
Luther A., Bisang C., Obrecht D. Advances in macrocyclic peptide-based antibiotics // Bioorganic and Medicinal Chemistry. 2018. Vol. 26. No. 10. pp. 2850-2858.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.bmc.2017.08.006
UR - https://doi.org/10.1016%2Fj.bmc.2017.08.006
TI - Advances in macrocyclic peptide-based antibiotics
T2 - Bioorganic and Medicinal Chemistry
AU - Luther, Anatol
AU - Bisang, Christian
AU - Obrecht, Daniel
PY - 2018
DA - 2018/06/01 00:00:00
PB - Elsevier
SP - 2850-2858
IS - 10
VL - 26
SN - 0968-0896
SN - 1464-3391
ER -
BibTex |
Cite this
BibTex Copy
@article{2018_Luther,
author = {Anatol Luther and Christian Bisang and Daniel Obrecht},
title = {Advances in macrocyclic peptide-based antibiotics},
journal = {Bioorganic and Medicinal Chemistry},
year = {2018},
volume = {26},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016%2Fj.bmc.2017.08.006},
number = {10},
pages = {2850--2858},
doi = {10.1016/j.bmc.2017.08.006}
}
MLA
Cite this
MLA Copy
Luther, Anatol, et al. “Advances in macrocyclic peptide-based antibiotics.” Bioorganic and Medicinal Chemistry, vol. 26, no. 10, Jun. 2018, pp. 2850-2858. https://doi.org/10.1016%2Fj.bmc.2017.08.006.
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