Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists
Тип публикации: Journal Article
Дата публикации: 2007-07-01
scimago Q2
wos Q2
БС2
SJR: 0.472
CiteScore: 5.1
Impact factor: 2.2
ISSN: 0960894X, 14643405
PubMed ID:
17521908
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Краткое описание
A novel series of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives were designed and synthesized as GnRH receptor antagonists. SAR studies led to a series of highly active molecules against both the rat and human receptors. Furthermore, one potent compound, 17j, demonstrated dose-dependent LH suppression in castrated rats.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Для доступа к списку цитирований публикации необходимо авторизоваться.
Топ-30
Журналы
|
1
2
|
|
|
Journal of Medicinal Chemistry
2 публикации, 20%
|
|
|
Bioorganic and Medicinal Chemistry Letters
1 публикация, 10%
|
|
|
Tetrahedron
1 публикация, 10%
|
|
|
Mendeleev Communications
1 публикация, 10%
|
|
|
Journal of Heterocyclic Chemistry
1 публикация, 10%
|
|
|
Medicinal Research Reviews
1 публикация, 10%
|
|
|
European Journal of Chemistry
1 публикация, 10%
|
|
|
Journal of Organic Chemistry
1 публикация, 10%
|
|
|
1
2
|
Издатели
|
1
2
3
|
|
|
Elsevier
3 публикации, 30%
|
|
|
American Chemical Society (ACS)
3 публикации, 30%
|
|
|
Wiley
2 публикации, 20%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 публикация, 10%
|
|
|
European Journal of Chemistry
1 публикация, 10%
|
|
|
1
2
3
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
10
Всего цитирований:
10
Цитирований c 2025:
1
(10%)
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Chen M. et al. Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists // Bioorganic and Medicinal Chemistry Letters. 2007. Vol. 17. No. 14. pp. 3845-3850.
ГОСТ со всеми авторами (до 50)
Скопировать
Chen M., Guo Z., Lanier M. C., Zhao L., Betz S. F., Huang C. Q., Loweth C. J., Ashweek N. J., Liu X., Struthers R. S., Bradbury M. J., Behan J. W., Wen J., O`Brien Z., Saunders J., Zhu Y. Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists // Bioorganic and Medicinal Chemistry Letters. 2007. Vol. 17. No. 14. pp. 3845-3850.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1016/j.bmcl.2007.05.009
UR - https://doi.org/10.1016/j.bmcl.2007.05.009
TI - Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists
T2 - Bioorganic and Medicinal Chemistry Letters
AU - Chen, Mi
AU - Guo, Zhiqiang
AU - Lanier, Marion C
AU - Zhao, Liren
AU - Betz, Stephen F
AU - Huang, Charles Q.
AU - Loweth, Colin J.
AU - Ashweek, Neil J
AU - Liu, X.
AU - Struthers, R Scott
AU - Bradbury, Margaret J.
AU - Behan, James W.
AU - Wen, Jenny
AU - O`Brien, Zhihong
AU - Saunders, John
AU - Zhu, Yun-Fei
PY - 2007
DA - 2007/07/01
PB - Elsevier
SP - 3845-3850
IS - 14
VL - 17
PMID - 17521908
SN - 0960-894X
SN - 1464-3405
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2007_Chen,
author = {Mi Chen and Zhiqiang Guo and Marion C Lanier and Liren Zhao and Stephen F Betz and Charles Q. Huang and Colin J. Loweth and Neil J Ashweek and X. Liu and R Scott Struthers and Margaret J. Bradbury and James W. Behan and Jenny Wen and Zhihong O`Brien and John Saunders and Yun-Fei Zhu},
title = {Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists},
journal = {Bioorganic and Medicinal Chemistry Letters},
year = {2007},
volume = {17},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.bmcl.2007.05.009},
number = {14},
pages = {3845--3850},
doi = {10.1016/j.bmcl.2007.05.009}
}
Цитировать
MLA
Скопировать
Chen, Mi, et al. “Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists.” Bioorganic and Medicinal Chemistry Letters, vol. 17, no. 14, Jul. 2007, pp. 3845-3850. https://doi.org/10.1016/j.bmcl.2007.05.009.