Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1
ZHANG WENMING
1
,
Caleb W Holyoke
1
,
Thomas F Pahutski
1
,
George P Lahm
1
,
James D. Barry
1
,
Daniel Cordova
1
,
ROBERT M. LEIGHTY
1
,
Vineet Singh
2, 3, 4
,
Daniel R Vicent
1
,
My Hanh T Tong
1
,
Kenneth A Hughes
1
,
Stephen F. McCann
1
,
Yewande T Henry
1
,
Ming Xu
1
,
Twyla A Briddell
1
1
DuPont Crop Protection, Stine-Haskell Research Center, 1094 Elkton Road, Newark, DE 19711, USA
|
2
E.I. DuPont India Pvt Ltd
3
South Asia Field Experimental Station
4
Vadodara Gujarat India
|
Publication type: Journal Article
Publication date: 2017-01-01
scimago Q2
wos Q2
SJR: 0.472
CiteScore: 5.1
Impact factor: 2.2
ISSN: 0960894X, 14643405
PubMed ID:
27894871
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species. In this communication, we report the part of the optimization program which led to the discovery of triflumezopyrim as a highly potent insecticide controlling various hopper species. Our efforts in discovery, synthesis, structure-activity relationship elucidation, and biological activity evaluation are also presented.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
2
4
6
8
10
12
14
16
|
|
|
Journal of Agricultural and Food Chemistry
16 publications, 31.37%
|
|
|
Chinese Chemical Letters
3 publications, 5.88%
|
|
|
Bioorganic and Medicinal Chemistry Letters
3 publications, 5.88%
|
|
|
Pest Management Science
3 publications, 5.88%
|
|
|
Molecules
2 publications, 3.92%
|
|
|
Organic Process Research and Development
2 publications, 3.92%
|
|
|
Advanced Synthesis and Catalysis
2 publications, 3.92%
|
|
|
Crystal Growth and Design
2 publications, 3.92%
|
|
|
Molecular Pharmacology
1 publication, 1.96%
|
|
|
PeerJ
1 publication, 1.96%
|
|
|
International Journal of Molecular Sciences
1 publication, 1.96%
|
|
|
Chemosphere
1 publication, 1.96%
|
|
|
Asian Journal of Organic Chemistry
1 publication, 1.96%
|
|
|
Accounts of Chemical Research
1 publication, 1.96%
|
|
|
Journal of Medicinal Chemistry
1 publication, 1.96%
|
|
|
Journal of Economic Entomology
1 publication, 1.96%
|
|
|
Zeitschrift fur Kristallographie - New Crystal Structures
1 publication, 1.96%
|
|
|
Annual Review of Pharmacology and Toxicology
1 publication, 1.96%
|
|
|
Advanced Agrochem
1 publication, 1.96%
|
|
|
Engineering
1 publication, 1.96%
|
|
|
Journal of Molecular Structure
1 publication, 1.96%
|
|
|
Russian Chemical Reviews
1 publication, 1.96%
|
|
|
Ecotoxicology and Environmental Safety
1 publication, 1.96%
|
|
|
2
4
6
8
10
12
14
16
|
Publishers
|
5
10
15
20
25
|
|
|
American Chemical Society (ACS)
22 publications, 43.14%
|
|
|
Elsevier
12 publications, 23.53%
|
|
|
Wiley
7 publications, 13.73%
|
|
|
MDPI
3 publications, 5.88%
|
|
|
American Society for Pharmacology and Experimental Therapeutics
1 publication, 1.96%
|
|
|
PeerJ
1 publication, 1.96%
|
|
|
Oxford University Press
1 publication, 1.96%
|
|
|
Walter de Gruyter
1 publication, 1.96%
|
|
|
Annual Reviews
1 publication, 1.96%
|
|
|
IntechOpen
1 publication, 1.96%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 1.96%
|
|
|
5
10
15
20
25
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
51
Total citations:
51
Citations from 2024:
14
(27.45%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
WENMING Z. et al. Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1 // Bioorganic and Medicinal Chemistry Letters. 2017. Vol. 27. No. 1. pp. 16-20.
GOST all authors (up to 50)
Copy
WENMING Z., Holyoke C. W., Pahutski T. F., Lahm G. P., Barry J. D., Cordova D., LEIGHTY R. M., Singh V., Vicent D. R., Tong M. H. T., Hughes K. A., McCann S. F., Henry Y. T., Xu M., Briddell T. A. Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1 // Bioorganic and Medicinal Chemistry Letters. 2017. Vol. 27. No. 1. pp. 16-20.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.bmcl.2016.11.042
UR - https://doi.org/10.1016/j.bmcl.2016.11.042
TI - Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1
T2 - Bioorganic and Medicinal Chemistry Letters
AU - WENMING, ZHANG
AU - Holyoke, Caleb W
AU - Pahutski, Thomas F
AU - Lahm, George P
AU - Barry, James D.
AU - Cordova, Daniel
AU - LEIGHTY, ROBERT M.
AU - Singh, Vineet
AU - Vicent, Daniel R
AU - Tong, My Hanh T
AU - Hughes, Kenneth A
AU - McCann, Stephen F.
AU - Henry, Yewande T
AU - Xu, Ming
AU - Briddell, Twyla A
PY - 2017
DA - 2017/01/01
PB - Elsevier
SP - 16-20
IS - 1
VL - 27
PMID - 27894871
SN - 0960-894X
SN - 1464-3405
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_WENMING,
author = {ZHANG WENMING and Caleb W Holyoke and Thomas F Pahutski and George P Lahm and James D. Barry and Daniel Cordova and ROBERT M. LEIGHTY and Vineet Singh and Daniel R Vicent and My Hanh T Tong and Kenneth A Hughes and Stephen F. McCann and Yewande T Henry and Ming Xu and Twyla A Briddell},
title = {Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1},
journal = {Bioorganic and Medicinal Chemistry Letters},
year = {2017},
volume = {27},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.bmcl.2016.11.042},
number = {1},
pages = {16--20},
doi = {10.1016/j.bmcl.2016.11.042}
}
Cite this
MLA
Copy
WENMING, ZHANG, et al. “Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1.” Bioorganic and Medicinal Chemistry Letters, vol. 27, no. 1, Jan. 2017, pp. 16-20. https://doi.org/10.1016/j.bmcl.2016.11.042.