, volume 241 , pages 116364

Hyaluronic acid—Based wound dressings: A review

Mariana F P Graça ¹

Cátia S D Cabral ¹

Ilídio J. Correia ^{2, 3}

Hide authors affiliations Show authors affiliations: 3 affiliations

CICS-UBI, Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal. |

CICS-UBI – Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal |

CIEPQPF – Departamento de Engenharia Química, Universidade de Coimbra, Rua Silvio Lima, 3030-790 Coimbra, Portugal |

Publication type: Journal Article

Publication date: 2020-08-01

Elsevier

Carbohydrate Polymers

scimago Q1

wos Q1

SJR: 2.004

CiteScore: 24.0

Impact factor: 12.5

ISSN: 01448617, 18791344

DOI: 10.1016/j.carbpol.2020.116364

Copy DOI

PubMed ID: 32507198

Materials Chemistry

Organic Chemistry

Polymers and Plastics

Abstract

Hyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process.

Found

2 citations

Demina Tatiana

🤝

DSc in Chemistry, associate professor

78 publications, 883 citations

h-index: 17

Moscow Aviation Institute (National Research University)

Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences

Sechenov First Moscow State Medical University

Nature-like technologies

1 citation

Klinov Dmitry

PhD in Physics and Mathematics

139 publications, 2 880 citations

h-index: 26

Moscow Institute of Physics and Technology

Research interests

Atomic force microscopy

Biomaterials

Biomedical composites

Biomedical nanocomposites

Biomedicine

Regenerative medicine

1 citation

Akopova Tatiana

81 publications, 1 033 citations, 20 reviews

h-index: 19

Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences

1 citation

Dubrovin Evgeniy

DSc in Physics and Mathematics

56 publications, 661 citations, 5 reviews

h-index: 14

Lomonosov Moscow State University

Sirius University of Science and Technology

1 citation

Stupin Viktor

107 publications, 949 citations

h-index: 15

Pirogov Russian National Research Medical University

1 citation

Tenchurin Timur

🥼 🤝

PhD in Chemistry

41 publications, 278 citations

h-index: 10

National Research Centre "Kurchatov Institute"

Research interests

Rheology

Tissue Engineering

1 citation

Barinov Nikolay

PhD in Physics and Mathematics

49 publications, 637 citations

h-index: 13

Lomonosov Moscow State University

Sirius University of Science and Technology

Moscow Institute of Physics and Technology

Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency

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