Current Opinion in Chemical Biology, volume 34, pages 80-87
The expanding world of DNA and RNA
Publication type: Journal Article
Publication date: 2016-10-01
Journal:
Current Opinion in Chemical Biology
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 7.8
ISSN: 13675931, 18790402
Biochemistry
Analytical Chemistry
Abstract
DNA and RNA are remarkable because they can both encode information and possess desired properties, including the ability to bind specific targets or catalyze specific reactions. Nucleotide modifications that do not interfere with enzymatic synthesis are now being used to bestow DNA or RNA with properties that further increase their utility, including phosphate and sugar modifications that increase nuclease resistance, nucleobase modifications that increase the range of activities possible, and even whole nucleobase replacement that results in selective pairing and the creation of unnatural base pairs that increase the information content. These modifications are increasingly being applied both in vitro and in vivo, including in efforts to create semi-synthetic organisms with altered or expanded genetic alphabets.
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Citations by publishers
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Wiley
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1 publication, 1.72%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 1.72%
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Chen T. et al. The expanding world of DNA and RNA // Current Opinion in Chemical Biology. 2016. Vol. 34. pp. 80-87.
GOST all authors (up to 50)
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Chen T., Hongdilokkul N., Liu Z., Thirunavukarasu D., Romesberg F. E. The expanding world of DNA and RNA // Current Opinion in Chemical Biology. 2016. Vol. 34. pp. 80-87.
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TY - JOUR
DO - 10.1016/j.cbpa.2016.08.001
UR - https://doi.org/10.1016/j.cbpa.2016.08.001
TI - The expanding world of DNA and RNA
T2 - Current Opinion in Chemical Biology
AU - Chen, Tingjian
AU - Hongdilokkul, Narupat
AU - Liu, Zhixia
AU - Thirunavukarasu, Deepak
AU - Romesberg, Floyd E.
PY - 2016
DA - 2016/10/01 00:00:00
PB - Elsevier
SP - 80-87
VL - 34
SN - 1367-5931
SN - 1879-0402
ER -
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@article{2016_Chen,
author = {Tingjian Chen and Narupat Hongdilokkul and Zhixia Liu and Deepak Thirunavukarasu and Floyd E. Romesberg},
title = {The expanding world of DNA and RNA},
journal = {Current Opinion in Chemical Biology},
year = {2016},
volume = {34},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/j.cbpa.2016.08.001},
pages = {80--87},
doi = {10.1016/j.cbpa.2016.08.001}
}