The development of RAPTA compounds for the treatment of tumors
Publication type: Journal Article
Publication date: 2016-01-01
scimago Q1
wos Q1
SJR: 4.638
CiteScore: 38.2
Impact factor: 23.5
ISSN: 00108545, 18733840
Materials Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Abstract
Ruthenium(II)-arene RAPTA-type compounds have been extensively explored for their medicinal properties. Herein a comprehensive review of this class of compounds is provided. A discussion of the basic RAPTA structure is given together with the ways it has been modified to elucidate the key role of each part and to afford targeted derivatives. The various mechanistic studies conducted on RAPTA compounds are described and these are linked to the observed macroscopic biological properties. Ultimately, the review shows that certain RAPTA compounds display quite unique properties that point towards a clinical investigation. (C) 2015 Elsevier B.V. All rights reserved.
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432
Total citations:
432
Citations from 2025:
36
(8.35%)
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Murray B. S. et al. The development of RAPTA compounds for the treatment of tumors // Coordination Chemistry Reviews. 2016. Vol. 306. pp. 86-114.
GOST all authors (up to 50)
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Murray B. S., Babak M. V., Hartinger C. G., Dyson P. J. The development of RAPTA compounds for the treatment of tumors // Coordination Chemistry Reviews. 2016. Vol. 306. pp. 86-114.
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TY - JOUR
DO - 10.1016/j.ccr.2015.06.014
UR - https://doi.org/10.1016/j.ccr.2015.06.014
TI - The development of RAPTA compounds for the treatment of tumors
T2 - Coordination Chemistry Reviews
AU - Murray, Benjamin S
AU - Babak, Maria V
AU - Hartinger, Christian G.
AU - Dyson, Paul J.
PY - 2016
DA - 2016/01/01
PB - Elsevier
SP - 86-114
VL - 306
SN - 0010-8545
SN - 1873-3840
ER -
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BibTex (up to 50 authors)
Copy
@article{2016_Murray,
author = {Benjamin S Murray and Maria V Babak and Christian G. Hartinger and Paul J. Dyson},
title = {The development of RAPTA compounds for the treatment of tumors},
journal = {Coordination Chemistry Reviews},
year = {2016},
volume = {306},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.ccr.2015.06.014},
pages = {86--114},
doi = {10.1016/j.ccr.2015.06.014}
}