Cell, volume 175, issue 3, pages 615-632

Stem Cells, Genome Editing, and the Path to Translational Medicine

Soldner Frank 1
Jaenisch Rudolf 2
1
 
The Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.
2
 
The Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA
Publication typeJournal Article
Publication date2018-10-18
Journal: Cell
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor64.5
ISSN00928674, 10974172
General Biochemistry, Genetics and Molecular Biology
Abstract
The derivation of human embryonic stem cells (hESCs) and the stunning discovery that somatic cells can be reprogrammed into human induced pluripotent stem cells (hiPSCs) holds the promise to revolutionize biomedical research and regenerative medicine. In this Review, we focus on disorders of the central nervous system and explore how advances in human pluripotent stem cells (hPSCs) coincide with evolutions in genome engineering and genomic technologies to provide realistic opportunities to tackle some of the most devastating complex disorders.

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GOST Copy
Soldner F., Jaenisch R. Stem Cells, Genome Editing, and the Path to Translational Medicine // Cell. 2018. Vol. 175. No. 3. pp. 615-632.
GOST all authors (up to 50) Copy
Soldner F., Jaenisch R. Stem Cells, Genome Editing, and the Path to Translational Medicine // Cell. 2018. Vol. 175. No. 3. pp. 615-632.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.cell.2018.09.010
UR - https://doi.org/10.1016%2Fj.cell.2018.09.010
TI - Stem Cells, Genome Editing, and the Path to Translational Medicine
T2 - Cell
AU - Soldner, Frank
AU - Jaenisch, Rudolf
PY - 2018
DA - 2018/10/18 00:00:00
PB - Elsevier
SP - 615-632
IS - 3
VL - 175
PMID - 30340033
SN - 0092-8674
SN - 1097-4172
ER -
BibTex |
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BibTex Copy
@article{2018_Soldner,
author = {Frank Soldner and Rudolf Jaenisch},
title = {Stem Cells, Genome Editing, and the Path to Translational Medicine},
journal = {Cell},
year = {2018},
volume = {175},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016%2Fj.cell.2018.09.010},
number = {3},
pages = {615--632},
doi = {10.1016/j.cell.2018.09.010}
}
MLA
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MLA Copy
Soldner, Frank, and Rudolf Jaenisch. “Stem Cells, Genome Editing, and the Path to Translational Medicine.” Cell, vol. 175, no. 3, Oct. 2018, pp. 615-632. https://doi.org/10.1016%2Fj.cell.2018.09.010.
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