Journal of Chromatography A, volume 1616, pages 460790

Microextraction approaches for bioanalytical applications: An overview

Mohamed Abdel-Rehim 1, 2
Stig Pedersen-Bjergaard 3
Abbi Abdel Rehim 4
Rafael Lucena 5
Mohammad Mahdi Moein 6
Soledad Cárdenas 5
Manuel Miró 7
5
 
Departamento de Química Analítica, Instituto Universitario de Investigación en Química Fina y Nanoquímica, Universidad de Córdoba, Campus de Rabanales, Edificio Marie Curie, Córdoba, E-14071, Spain.
7
 
FI-TRACE Group, Department of Chemistry, University of the Balearic Islands, Carretera de Valldemossa km 7.5, Palma de Mallorca, 07122, Spain.
Publication typeJournal Article
Publication date2020-04-01
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.1
ISSN00219673, 18733778
Organic Chemistry
Biochemistry
General Medicine
Analytical Chemistry
Abstract
Biological samples are usually complex matrices due to the presence of proteins, salts and a variety of organic compounds with chemical properties similar to those of the target analytes. Therefore, sample preparation is often mandatory in order to isolate the analytes from troublesome matrices before instrumental analysis. Because the number of samples in drug development, doping analysis, forensic science, toxicological analysis, and preclinical and clinical assays is steadily increasing, novel high throughput sample preparation approaches are calling for. The key factors in this development are the miniaturization and the automation of the sample preparation approaches so as to cope with most of the twelve principles of green chemistry. In this review, recent trends in sample preparation and novel strategies will be discussed in detail with particular focus on sorptive and liquid-phase microextraction in bioanalysis. The actual applicability of selective sorbents is also considered. Additionally, the role of 3D printing in microextraction for bioanalytical methods will be pinpointed.

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Abdel-Rehim M. et al. Microextraction approaches for bioanalytical applications: An overview // Journal of Chromatography A. 2020. Vol. 1616. p. 460790.
GOST all authors (up to 50) Copy
Abdel-Rehim M., Pedersen-Bjergaard S., Abdel Rehim A., Lucena R., Moein M. M., Cárdenas S., Miró M. Microextraction approaches for bioanalytical applications: An overview // Journal of Chromatography A. 2020. Vol. 1616. p. 460790.
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RIS Copy
TY - JOUR
DO - 10.1016/j.chroma.2019.460790
UR - https://doi.org/10.1016/j.chroma.2019.460790
TI - Microextraction approaches for bioanalytical applications: An overview
T2 - Journal of Chromatography A
AU - Abdel-Rehim, Mohamed
AU - Pedersen-Bjergaard, Stig
AU - Abdel Rehim, Abbi
AU - Lucena, Rafael
AU - Moein, Mohammad Mahdi
AU - Cárdenas, Soledad
AU - Miró, Manuel
PY - 2020
DA - 2020/04/01 00:00:00
PB - Elsevier
SP - 460790
VL - 1616
SN - 0021-9673
SN - 1873-3778
ER -
BibTex
Cite this
BibTex Copy
@article{2020_Abdel-Rehim,
author = {Mohamed Abdel-Rehim and Stig Pedersen-Bjergaard and Abbi Abdel Rehim and Rafael Lucena and Mohammad Mahdi Moein and Soledad Cárdenas and Manuel Miró},
title = {Microextraction approaches for bioanalytical applications: An overview},
journal = {Journal of Chromatography A},
year = {2020},
volume = {1616},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/j.chroma.2019.460790},
pages = {460790},
doi = {10.1016/j.chroma.2019.460790}
}
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