European Journal of Medicinal Chemistry

, volume 40 , issue 12 , pages 1335-1340

Synthesis and antimalarial activities of some furoxan sulfones and related furazans

Ubaldina Galli ¹

Loretta Lazzarato ²

Massimo Bertinaria ²

Giovanni Sorba ¹

Alberto Gasco ²

Nicoletta Basilico ³

Donatella Taramelli ³

Hide authors affiliations Show authors affiliations: 3 affiliations

Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Università degli Studi del Piemonte Orientale, via Bovio 6, 28100 Novara, Italy. |

Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria, 9‐10125 Torino, Italy |

Istituto di Microbiologia, Università degli Studi di Milano, Via Pascal 36, 20133 Milano, Italy |

Publication type: Journal Article

Publication date: 2005-12-01

Elsevier

European Journal of Medicinal Chemistry

scimago Q1

wos Q1

SJR: 1.142

CiteScore: 11.3

Impact factor: 5.9

ISSN: 02235234, 17683254

DOI: 10.1016/j.ejmech.2005.05.001

Copy DOI

PubMed ID: 15979766

Organic Chemistry

Drug Discovery

General Medicine

Pharmacology

Abstract

Furoxan derivatives bearing a sulfone moiety at position 3 or 4 were synthesized and tested for their antimalarial action on the chloroquine-sensitive D10 and the chloroquine-resistant W2 strains of Plasmodium falciparum. The furazan analogues were considered for comparison. The most active compounds were the products in which the -SO2R groups are at the 3-position of the furoxan system. These latter substances displayed an antimalarial activity in the microM range, possibly related in part to their ability to release NO.

Found

2 citations

Rolando Barbara

112 publications, 2 487 citations

h-index: 29

University of Turin

1 citation

Fershtat Leonid

DSc in Chemistry

147 publications, 3 005 citations, 121 reviews

h-index: 29

N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences

Top-30

Journals

Publishers

	2 4 6 8 10 12
Elsevier	Elsevier, 12, 33.33% Elsevier 12 publications, 33.33%
Wiley	Wiley, 7, 19.44% Wiley 7 publications, 19.44%
American Chemical Society (ACS)	American Chemical Society (ACS), 3, 8.33% American Chemical Society (ACS) 3 publications, 8.33%
Springer Nature	Springer Nature, 2, 5.56% Springer Nature 2 publications, 5.56%
Pleiades Publishing	Pleiades Publishing, 2, 5.56% Pleiades Publishing 2 publications, 5.56%
Taylor & Francis	Taylor & Francis, 2, 5.56% Taylor & Francis 2 publications, 5.56%
American Society for Microbiology	American Society for Microbiology, 2, 5.56% American Society for Microbiology 2 publications, 5.56%
Beilstein-Institut	Beilstein-Institut, 1, 2.78% Beilstein-Institut 1 publication, 2.78%
Korean Chemical Society	Korean Chemical Society, 1, 2.78% Korean Chemical Society 1 publication, 2.78%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 2.78% Royal Society of Chemistry (RSC) 1 publication, 2.78%
Science Alert	Science Alert, 1, 2.78% Science Alert 1 publication, 2.78%
Bentham Science Publishers Ltd.	Bentham Science Publishers Ltd., 1, 2.78% Bentham Science Publishers Ltd. 1 publication, 2.78%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii	Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii, 1, 2.78% Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii 1 publication, 2.78%
	2 4 6 8 10 12

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

Metrics

Cite this

GOST |

Cite this

GOST Copy

Galli U. et al. Synthesis and antimalarial activities of some furoxan sulfones and related furazans // European Journal of Medicinal Chemistry. 2005. Vol. 40. No. 12. pp. 1335-1340.

GOST all authors (up to 50) Copy

Galli U., Lazzarato L., Bertinaria M., Sorba G., Gasco A., Basilico N., Taramelli D. Synthesis and antimalarial activities of some furoxan sulfones and related furazans // European Journal of Medicinal Chemistry. 2005. Vol. 40. No. 12. pp. 1335-1340.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.ejmech.2005.05.001

UR - https://doi.org/10.1016/j.ejmech.2005.05.001

TI - Synthesis and antimalarial activities of some furoxan sulfones and related furazans

T2 - European Journal of Medicinal Chemistry

AU - Galli, Ubaldina

AU - Lazzarato, Loretta

AU - Bertinaria, Massimo

AU - Sorba, Giovanni

AU - Gasco, Alberto

AU - Basilico, Nicoletta

AU - Taramelli, Donatella

PY - 2005

DA - 2005/12/01

PB - Elsevier

SP - 1335-1340

IS - 12

VL - 40

PMID - 15979766

SN - 0223-5234

SN - 1768-3254

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2005_Galli,

author = {Ubaldina Galli and Loretta Lazzarato and Massimo Bertinaria and Giovanni Sorba and Alberto Gasco and Nicoletta Basilico and Donatella Taramelli},

title = {Synthesis and antimalarial activities of some furoxan sulfones and related furazans},

journal = {European Journal of Medicinal Chemistry},

year = {2005},

volume = {40},

publisher = {Elsevier},

month = {dec},

url = {https://doi.org/10.1016/j.ejmech.2005.05.001},

number = {12},

pages = {1335--1340},

doi = {10.1016/j.ejmech.2005.05.001}

}

MLA

Cite this

MLA Copy

Galli, Ubaldina, et al. “Synthesis and antimalarial activities of some furoxan sulfones and related furazans.” European Journal of Medicinal Chemistry, vol. 40, no. 12, Dec. 2005, pp. 1335-1340. https://doi.org/10.1016/j.ejmech.2005.05.001.

Publisher

Elsevier

Journal

European Journal of Medicinal Chemistry

scimago Q1

wos Q1

SJR

1.142

CiteScore

11.3

Impact factor

5.9

ISSN

02235234 (Print)

17683254 (Electronic)