volume 142 pages 523-549

1,3,5-Triazines: A promising scaffold for anticancer drugs development

Stella Cascioferro 1
Barbara Parrino 1
Virginia Spanò 1
Anna Carbone 1
Alessandra Montalbano 1
Paola Barraja 1
Patrizia Diana 1
Girolamo Cirrincione 1
Publication typeJournal Article
Publication date2017-12-01
scimago Q1
wos Q1
SJR1.142
CiteScore11.3
Impact factor5.9
ISSN02235234, 17683254
Organic Chemistry
Drug Discovery
General Medicine
Pharmacology
Abstract
This review covering literature reports from the beginning of this century to 2016 describes the synthetic pathways, the antitumor activity, the structure-activity relationship and, whenever reported, the possible mechanism of action of 1,3,5-triazine derivatives as well as of their hetero-fused compounds. Many 1,3,5-triazine derivatives, both uncondensed and hetero-fused, have shown remarkable antitumor activities and some of them reached clinical development.
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GOST |
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GOST Copy
Cascioferro S. et al. 1,3,5-Triazines: A promising scaffold for anticancer drugs development // European Journal of Medicinal Chemistry. 2017. Vol. 142. pp. 523-549.
GOST all authors (up to 50) Copy
Cascioferro S., Parrino B., Spanò V., Carbone A., Montalbano A., Barraja P., Diana P., Cirrincione G. 1,3,5-Triazines: A promising scaffold for anticancer drugs development // European Journal of Medicinal Chemistry. 2017. Vol. 142. pp. 523-549.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.ejmech.2017.09.035
UR - https://doi.org/10.1016/j.ejmech.2017.09.035
TI - 1,3,5-Triazines: A promising scaffold for anticancer drugs development
T2 - European Journal of Medicinal Chemistry
AU - Cascioferro, Stella
AU - Parrino, Barbara
AU - Spanò, Virginia
AU - Carbone, Anna
AU - Montalbano, Alessandra
AU - Barraja, Paola
AU - Diana, Patrizia
AU - Cirrincione, Girolamo
PY - 2017
DA - 2017/12/01
PB - Elsevier
SP - 523-549
VL - 142
PMID - 29046238
SN - 0223-5234
SN - 1768-3254
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2017_Cascioferro,
author = {Stella Cascioferro and Barbara Parrino and Virginia Spanò and Anna Carbone and Alessandra Montalbano and Paola Barraja and Patrizia Diana and Girolamo Cirrincione},
title = {1,3,5-Triazines: A promising scaffold for anticancer drugs development},
journal = {European Journal of Medicinal Chemistry},
year = {2017},
volume = {142},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.ejmech.2017.09.035},
pages = {523--549},
doi = {10.1016/j.ejmech.2017.09.035}
}