Food Bioscience, volume 47, pages 101632

Octacosanol and health benefits: Biological functions and mechanisms of action

Feijun Luo ¹

Fuliang Cao ²

Fei-Jun Luo ¹

Qinlu Lin ¹

Hide authors affiliations Show authors affiliations: 2 affiliations

National Engineering Laboratory for Deep Process of Rice and Byproducts, Hunan Key Laboratory of Grain-oil Deep Process and Quality Control, Hunan Key Laboratory of Processed Food for Special Medical Purpose, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, 410004, Hunan, China |

Co-innovation Center for the Sustainable Forestry in Southern China, College of Forestry, Nanjing Forestry University, Nanjing, 210037, Jiangsu, China |

Publication type: Journal Article

Publication date: 2022-06-01

Elsevier

Journal: Food Bioscience

Quartile SCImago

Quartile WOS

Impact factor: 5.2

ISSN: 22124292, 22124306

DOI: 10.1016/j.fbio.2022.101632

Copy DOI

Biochemistry

Food Science

Abstract

Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and purified from rice bran, sugarcane, beeswax, insect wax, etc. Octacosanol exerts various biological effects, including anti-fatigue, anti-hypoxia, antioxidant, anti-inflammatory, antitumor, etc. Meanwhile, it has the effects of regulating the body's immune function and energy metabolism and has potential benefits for cardiovascular disease, cerebrovascular disorders, diabetes, Parkinson's disease, and others. Octacosanol is primarily responsible for regulating multiple signaling pathways, such as AMPK, PI3K/Akt, and MAPK/NF-κB, to achieve different physiological functions. This review systemically summarized the progress in characterization, extraction and purification, biological functions, molecular mechanisms, and bioavailability of octacosanol. This study will provide a reference for many investigators to further explore the physiological functions of higher aliphatic alcohols and apply them as supplements in functional foods. The natural sources and biological functions of octacosanol.

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Citations by journals

	1
Foods	Foods, 1, 5.56% Foods 1 publication, 5.56%
Sustainability	Sustainability, 1, 5.56% Sustainability 1 publication, 5.56%
Coatings	Coatings, 1, 5.56% Coatings 1 publication, 5.56%
Revista Brasileira de Farmacognosia	Revista Brasileira de Farmacognosia, 1, 5.56% Revista Brasileira de Farmacognosia 1 publication, 5.56%
Green Chemistry	Green Chemistry, 1, 5.56% Green Chemistry 1 publication, 5.56%
Brazilian Journal of Food Technology	Brazilian Journal of Food Technology, 1, 5.56% Brazilian Journal of Food Technology 1 publication, 5.56%
Journal of Medical Biochemistry	Journal of Medical Biochemistry, 1, 5.56% Journal of Medical Biochemistry 1 publication, 5.56%
IOP Conference Series: Earth and Environmental Science	IOP Conference Series: Earth and Environmental Science, 1, 5.56% IOP Conference Series: Earth and Environmental Science 1 publication, 5.56%
Biocatalysis and Agricultural Biotechnology	Biocatalysis and Agricultural Biotechnology, 1, 5.56% Biocatalysis and Agricultural Biotechnology 1 publication, 5.56%
International Journal of Pharmaceutics	International Journal of Pharmaceutics, 1, 5.56% International Journal of Pharmaceutics 1 publication, 5.56%
Aquaculture International	Aquaculture International, 1, 5.56% Aquaculture International 1 publication, 5.56%
EPMA Journal	EPMA Journal, 1, 5.56% EPMA Journal 1 publication, 5.56%
Current Microbiology	Current Microbiology, 1, 5.56% Current Microbiology 1 publication, 5.56%
Process Safety and Environmental Protection	Process Safety and Environmental Protection, 1, 5.56% Process Safety and Environmental Protection 1 publication, 5.56%
Food Bioengineering	Food Bioengineering, 1, 5.56% Food Bioengineering 1 publication, 5.56%
Journal of Animal Physiology and Animal Nutrition	Journal of Animal Physiology and Animal Nutrition, 1, 5.56% Journal of Animal Physiology and Animal Nutrition 1 publication, 5.56%
Colloids and Surfaces B: Biointerfaces	Colloids and Surfaces B: Biointerfaces, 1, 5.56% Colloids and Surfaces B: Biointerfaces 1 publication, 5.56%
Pharmaceuticals	Pharmaceuticals, 1, 5.56% Pharmaceuticals 1 publication, 5.56%
	1

Citations by publishers

	1 2 3 4
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 4, 22.22% Multidisciplinary Digital Publishing Institute (MDPI) 4 publications, 22.22%
Springer Nature	Springer Nature, 4, 22.22% Springer Nature 4 publications, 22.22%
Elsevier	Elsevier, 4, 22.22% Elsevier 4 publications, 22.22%
Wiley	Wiley, 2, 11.11% Wiley 2 publications, 11.11%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 5.56% Royal Society of Chemistry (RSC) 1 publication, 5.56%
Instituto de Tecnologia de Alimentos (ITAL)	Instituto de Tecnologia de Alimentos (ITAL), 1, 5.56% Instituto de Tecnologia de Alimentos (ITAL) 1 publication, 5.56%
Society of Medical Biochemists of Serbia	Society of Medical Biochemists of Serbia, 1, 5.56% Society of Medical Biochemists of Serbia 1 publication, 5.56%
IOP Publishing	IOP Publishing, 1, 5.56% IOP Publishing 1 publication, 5.56%
	1 2 3 4

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Luo F. et al. Octacosanol and health benefits: Biological functions and mechanisms of action // Food Bioscience. 2022. Vol. 47. p. 101632.

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Luo F., Cao F., Luo F., Lin Q. Octacosanol and health benefits: Biological functions and mechanisms of action // Food Bioscience. 2022. Vol. 47. p. 101632.

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RIS Copy

TY - JOUR

DO - 10.1016/j.fbio.2022.101632

UR - https://doi.org/10.1016/j.fbio.2022.101632

TI - Octacosanol and health benefits: Biological functions and mechanisms of action

T2 - Food Bioscience

AU - Luo, Feijun

AU - Cao, Fuliang

AU - Luo, Fei-Jun

AU - Lin, Qinlu

PY - 2022

DA - 2022/06/01 00:00:00

PB - Elsevier

SP - 101632

VL - 47

SN - 2212-4292

SN - 2212-4306

ER -

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BibTex Copy

@article{2022_Luo,

author = {Feijun Luo and Fuliang Cao and Fei-Jun Luo and Qinlu Lin},

title = {Octacosanol and health benefits: Biological functions and mechanisms of action},

journal = {Food Bioscience},

year = {2022},

volume = {47},

publisher = {Elsevier},

month = {jun},

url = {https://doi.org/10.1016/j.fbio.2022.101632},

pages = {101632},

doi = {10.1016/j.fbio.2022.101632}

}

Found error?

Publisher

Elsevier

Journal

Food Bioscience

Quartile SCImago

Quartile WOS

Impact factor

5.2

ISSN

22124292 (Print)
22124306 (Electronic)