Fitoterapia, volume 142, pages 104491

Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia

Huo Zong Qing ¹

Zhao Qian Ping ²

Liu Jianwen ²

Zhu Wentao ²

Hao Xiao-Jiang ²

Zhang Yu ²

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University of Chinese Academy of Sciences,Beijing 100049,PR China |

State Key Laboratory of Phytochemistry & Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China. |

Publication type: Journal Article

Publication date: 2020-04-01

Elsevier

Journal: Fitoterapia

Quartile SCImago

Quartile WOS

Impact factor: 3.4

ISSN: 0367326X, 18736971

DOI: 10.1016/j.fitote.2020.104491

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Drug Discovery

General Medicine

Pharmacology

Abstract

Two new monoterpenoid indole alkaloids, bousangines A (1) and B (2), were isolated from the twigs and leaves of Bousigonia angustifolia. Their structures including absolute configurations were elucidated by a combination of MS, NMR, ECD calculation, and single-crystal X-ray diffraction analysis. Bousangine A (1) possessed a rearrangement pentacyclic skeleton derived from aspidosperma-type alkaloids with C-17 degradation. Their antiproliferative activity against several human cancer cell lines were evaluated.

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	1
Current Topics in Medicinal Chemistry	Current Topics in Medicinal Chemistry, 1, 14.29% Current Topics in Medicinal Chemistry 1 publication, 14.29%
Chemistry of Natural Compounds	Chemistry of Natural Compounds, 1, 14.29% Chemistry of Natural Compounds 1 publication, 14.29%
Natural Products and Bioprospecting	Natural Products and Bioprospecting, 1, 14.29% Natural Products and Bioprospecting 1 publication, 14.29%
Phytochemistry	Phytochemistry, 1, 14.29% Phytochemistry 1 publication, 14.29%
Fitoterapia	Fitoterapia, 1, 14.29% Fitoterapia 1 publication, 14.29%
Phytochemistry Letters	Phytochemistry Letters, 1, 14.29% Phytochemistry Letters 1 publication, 14.29%
Naunyn-Schmiedeberg's Archives of Pharmacology	Naunyn-Schmiedeberg's Archives of Pharmacology, 1, 14.29% Naunyn-Schmiedeberg's Archives of Pharmacology 1 publication, 14.29%
	1

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Springer Nature	Springer Nature, 3, 42.86% Springer Nature 3 publications, 42.86%
Elsevier	Elsevier, 3, 42.86% Elsevier 3 publications, 42.86%
Bentham Science	Bentham Science, 1, 14.29% Bentham Science 1 publication, 14.29%
	1 2 3

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Huo Z. Q. et al. Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia // Fitoterapia. 2020. Vol. 142. p. 104491.

GOST all authors (up to 50) Copy

Huo Z. Q., Zhao Q. P., Liu J., Zhu W., Hao X., Zhang Yu. Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia // Fitoterapia. 2020. Vol. 142. p. 104491.

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RIS Copy

TY - JOUR

DO - 10.1016/j.fitote.2020.104491

UR - https://doi.org/10.1016/j.fitote.2020.104491

TI - Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia

T2 - Fitoterapia

AU - Huo, Zong Qing

AU - Zhao, Qian Ping

AU - Liu, Jianwen

AU - Zhu, Wentao

AU - Hao, Xiao-Jiang

AU - Zhang, Yu

PY - 2020

DA - 2020/04/01 00:00:00

PB - Elsevier

SP - 104491

VL - 142

SN - 0367-326X

SN - 1873-6971

ER -

BibTex

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BibTex Copy

@article{2020_Huo,

author = {Zong Qing Huo and Qian Ping Zhao and Jianwen Liu and Wentao Zhu and Xiao-Jiang Hao and Yu Zhang},

title = {Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia},

journal = {Fitoterapia},

year = {2020},

volume = {142},

publisher = {Elsevier},

month = {apr},

url = {https://doi.org/10.1016/j.fitote.2020.104491},

pages = {104491},

doi = {10.1016/j.fitote.2020.104491}

}

Found error?

Publisher

Elsevier

Journal

Fitoterapia

Quartile SCImago

Quartile WOS

Impact factor

3.4

ISSN

0367326X (Print)
18736971 (Electronic)