Thixotropic property in pharmaceutical formulations
Publication type: Journal Article
Publication date: 2009-06-01
scimago Q1
wos Q1
SJR: 2.470
CiteScore: 19.4
Impact factor: 11.5
ISSN: 01683659, 18734995
PubMed ID:
19250955
Pharmaceutical Science
Abstract
This review focuses on the characterization of the thixotropic property, the factors affecting the thixotropic property and its pharmaceutical applications. These factors include pH, temperature, polymer concentrations, polymer modification, polymer combinations, and addition of cations or excipients. The relationships between the rheological properties of thixotropic formulations, and their effects on the controlled drug delivery through various routes including oral, topical, ophthalmic, dental and mucosal administration and pharmacological efficacies were also discussed. The comprehensive analysis of rheological and mechanical properties will provide an insight into the potential usage of thixotropic formulations as drug delivery systems.
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Metrics
328
Total citations:
328
Citations from 2025:
34
(10.36%)
Cite this
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MLA
Cite this
GOST
Copy
Lee C. H., Moturi V., Lee Y. Thixotropic property in pharmaceutical formulations // Journal of Controlled Release. 2009. Vol. 136. No. 2. pp. 88-98.
GOST all authors (up to 50)
Copy
Lee C. H., Moturi V., Lee Y. Thixotropic property in pharmaceutical formulations // Journal of Controlled Release. 2009. Vol. 136. No. 2. pp. 88-98.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.jconrel.2009.02.013
UR - https://doi.org/10.1016/j.jconrel.2009.02.013
TI - Thixotropic property in pharmaceutical formulations
T2 - Journal of Controlled Release
AU - Lee, Chi H.
AU - Moturi, Venkat
AU - Lee, Yugyung
PY - 2009
DA - 2009/06/01
PB - Elsevier
SP - 88-98
IS - 2
VL - 136
PMID - 19250955
SN - 0168-3659
SN - 1873-4995
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2009_Lee,
author = {Chi H. Lee and Venkat Moturi and Yugyung Lee},
title = {Thixotropic property in pharmaceutical formulations},
journal = {Journal of Controlled Release},
year = {2009},
volume = {136},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016/j.jconrel.2009.02.013},
number = {2},
pages = {88--98},
doi = {10.1016/j.jconrel.2009.02.013}
}
Cite this
MLA
Copy
Lee, Chi H., et al. “Thixotropic property in pharmaceutical formulations.” Journal of Controlled Release, vol. 136, no. 2, Jun. 2009, pp. 88-98. https://doi.org/10.1016/j.jconrel.2009.02.013.