Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori
Publication type: Journal Article
Publication date: 2009-07-01
scimago Q1
wos Q1
SJR: 1.142
CiteScore: 10.4
Impact factor: 5.4
ISSN: 03788741, 18727573
PubMed ID:
19422904
Drug Discovery
Pharmacology
Abstract
The increasing resistance of Helicobacter pylori to antibiotics demands the search for novel compounds from plant based sources. Artemisia douglasiana Besser is widely used in Cuyo region (Argentina) as folk medicine for the treatment of gastric ailments.Based on our previous studies that Artemisia douglasiana exert cytoprotective actions against ethanol-induced gastric mucosal injury we assayed the anti-Helicobacter pylori effect of the Artemisia douglasiana extract and its active compound, dehydroleucodine.The in vitro anti-bacterial activity of Artemisia douglasiana extract and its active compound, dehydroleucodine were determined against one standard strain and six clinical isolates of Helicobacter pylori by using the agar dilution methods.The results showed that both dehydroleucodine and Artemisia douglasiana extract had activity against the microorganism with MICs between 1-8 and 60-120 mg/L, respectively.Artemisia douglasiana may be a useful alternative treatment strategy principally in eradication of metronidazole and clarithromycin-resistant strain.
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GOST
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Vega A. et al. Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori // Journal of Ethnopharmacology. 2009. Vol. 124. No. 3. pp. 653-655.
GOST all authors (up to 50)
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Vega A., Wendel G. H., Maria A. O. M., Pelzer L. Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori // Journal of Ethnopharmacology. 2009. Vol. 124. No. 3. pp. 653-655.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.jep.2009.04.051
UR - https://doi.org/10.1016/j.jep.2009.04.051
TI - Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori
T2 - Journal of Ethnopharmacology
AU - Vega, Alba
AU - Wendel, G H
AU - Maria, A O M
AU - Pelzer, L
PY - 2009
DA - 2009/07/01
PB - Elsevier
SP - 653-655
IS - 3
VL - 124
PMID - 19422904
SN - 0378-8741
SN - 1872-7573
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2009_Vega,
author = {Alba Vega and G H Wendel and A O M Maria and L Pelzer},
title = {Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori},
journal = {Journal of Ethnopharmacology},
year = {2009},
volume = {124},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.jep.2009.04.051},
number = {3},
pages = {653--655},
doi = {10.1016/j.jep.2009.04.051}
}
Cite this
MLA
Copy
Vega, Alba, et al. “Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori.” Journal of Ethnopharmacology, vol. 124, no. 3, Jul. 2009, pp. 653-655. https://doi.org/10.1016/j.jep.2009.04.051.