Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates
3
C.N.R.—Istituto di Chimica del Riconoscimento Molecolare, sezione “A. Quilico”, via Mancinelli 7, I-20131 Milan, Italy
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Publication type: Journal Article
Publication date: 2004-04-19
scimago Q3
wos Q3
SJR: 0.333
CiteScore: 3.7
Impact factor: 1.9
ISSN: 00221139, 18733328
Organic Chemistry
Biochemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Environmental Chemistry
Abstract
We describe the first synthesis of enantiomerically pure (S)-α-vinyl and (S)-α-ethynyl 3,3,3-trifluoro alanine (TF-Ala) ethyl esters, starting from the in situ generated sulfinimine (S)-2 as key fluorinated building-block. (S)-α-Ethyl TF-Ala-OEt has been prepared as well by this route.
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36
Total citations:
36
Citations from 2024:
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(2.78%)
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GOST
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Crucianelli M. et al. Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates // Journal of Fluorine Chemistry. 2004. Vol. 125. No. 4. pp. 573-577.
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Crucianelli M., De Angelis F., Lazzaro F., Malpezzi L., Volonterio A., Zanda M. Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates // Journal of Fluorine Chemistry. 2004. Vol. 125. No. 4. pp. 573-577.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.jfluchem.2003.11.034
UR - https://doi.org/10.1016/j.jfluchem.2003.11.034
TI - Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates
T2 - Journal of Fluorine Chemistry
AU - Crucianelli, M.
AU - De Angelis, Francesco
AU - Lazzaro, Francesco
AU - Malpezzi, Luciana
AU - Volonterio, A.
AU - Zanda, M.
PY - 2004
DA - 2004/04/19
PB - Elsevier
SP - 573-577
IS - 4
VL - 125
SN - 0022-1139
SN - 1873-3328
ER -
Cite this
BibTex (up to 50 authors)
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@article{2004_Crucianelli,
author = {M. Crucianelli and Francesco De Angelis and Francesco Lazzaro and Luciana Malpezzi and A. Volonterio and M. Zanda},
title = {Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates},
journal = {Journal of Fluorine Chemistry},
year = {2004},
volume = {125},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/j.jfluchem.2003.11.034},
number = {4},
pages = {573--577},
doi = {10.1016/j.jfluchem.2003.11.034}
}
Cite this
MLA
Copy
Crucianelli, M., et al. “Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates.” Journal of Fluorine Chemistry, vol. 125, no. 4, Apr. 2004, pp. 573-577. https://doi.org/10.1016/j.jfluchem.2003.11.034.
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