Synthesis and anticancer activity of cyclopalladated complexes containing 4-hydroxy-acridine
Daniela Pucci
1
,
Veronica Albertini
2
,
Rossana Bloise
3
,
Anna Bellusci
3
,
Antonella Cataldi
3
,
Carlo V Catapano
2
,
M. Ghedini
3
,
ALESSANDRA CRISPINI
1
1
Тип публикации: Journal Article
Дата публикации: 2006-09-01
scimago Q2
wos Q2
БС1
SJR: 0.621
CiteScore: 7.0
Impact factor: 3.2
ISSN: 01620134, 18733344
PubMed ID:
16828871
Biochemistry
Inorganic Chemistry
Краткое описание
The synthesis and the characterization (elemental analysis, 1 H NMR and X-ray) of the first cyclopalladated complexes containing 4-hydroxyacridinate as complementary ligand are described. 4-Hydroxyacridine acts as a bidentate [N,O] chelating ligand, giving rise to square planar Pd(II) complexes in the coordination of a cyclopalladated fragment of phenylpyridine or phenylpyrimidine, characterized by the presence of two almost coplanar metalated rings. The biological activity studies conducted on these new Pd(II) complexes proved that the phenylpyridine Pd(II) derivative is more efficient than cis -platinum. The intrinsically substitutional inertness of the cyclopalladated ring and the presence of the [N,O] chelated acridine ligand make these systems of particular interest in their promising biological activity.
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Pucci D. et al. Synthesis and anticancer activity of cyclopalladated complexes containing 4-hydroxy-acridine // Journal of Inorganic Biochemistry. 2006. Vol. 100. No. 9. pp. 1575-1578.
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Pucci D., Albertini V., Bloise R., Bellusci A., Cataldi A., Catapano C. V., Ghedini M., CRISPINI A. Synthesis and anticancer activity of cyclopalladated complexes containing 4-hydroxy-acridine // Journal of Inorganic Biochemistry. 2006. Vol. 100. No. 9. pp. 1575-1578.
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TY - JOUR
DO - 10.1016/j.jinorgbio.2006.04.009
UR - https://doi.org/10.1016/j.jinorgbio.2006.04.009
TI - Synthesis and anticancer activity of cyclopalladated complexes containing 4-hydroxy-acridine
T2 - Journal of Inorganic Biochemistry
AU - Pucci, Daniela
AU - Albertini, Veronica
AU - Bloise, Rossana
AU - Bellusci, Anna
AU - Cataldi, Antonella
AU - Catapano, Carlo V
AU - Ghedini, M.
AU - CRISPINI, ALESSANDRA
PY - 2006
DA - 2006/09/01
PB - Elsevier
SP - 1575-1578
IS - 9
VL - 100
PMID - 16828871
SN - 0162-0134
SN - 1873-3344
ER -
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@article{2006_Pucci,
author = {Daniela Pucci and Veronica Albertini and Rossana Bloise and Anna Bellusci and Antonella Cataldi and Carlo V Catapano and M. Ghedini and ALESSANDRA CRISPINI},
title = {Synthesis and anticancer activity of cyclopalladated complexes containing 4-hydroxy-acridine},
journal = {Journal of Inorganic Biochemistry},
year = {2006},
volume = {100},
publisher = {Elsevier},
month = {sep},
url = {https://doi.org/10.1016/j.jinorgbio.2006.04.009},
number = {9},
pages = {1575--1578},
doi = {10.1016/j.jinorgbio.2006.04.009}
}
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MLA
Скопировать
Pucci, Daniela, et al. “Synthesis and anticancer activity of cyclopalladated complexes containing 4-hydroxy-acridine.” Journal of Inorganic Biochemistry, vol. 100, no. 9, Sep. 2006, pp. 1575-1578. https://doi.org/10.1016/j.jinorgbio.2006.04.009.