Journal of Inorganic Biochemistry, volume 167, pages 80-88
Low-dimensional compounds containing bioactive ligands. Part VIII: DNA interaction, antimicrobial and antitumor activities of ionic 5,7-dihalo-8-quinolinolato palladium(II) complexes with K+ and Cs+ cations
Veronika Farkasova
1
,
Sayed Ali Drweesh
2
,
Andrea Lüköová
1
,
Danica Sabolová
3
,
Ivana Radojevic
4
,
Ljiljana Comic
4
,
Sava M Vasić
4
,
Helena Paulikova
5
,
Stanislav Fečko
5
,
Tatiana Balašková
5
,
Mária Vilková
6
,
Ján Imrich
6
,
1
Department of Inorganic Chemistry, Institute of Chemistry, P. J. Šafárik University, Moyzesova 11, 041 54 Košice, Slovakia
|
2
Department of Inorganic Chemistry, National Research Center, P.O. 12622, 33 Elbohoth St. (former Elthrirst), Dokki, Giza, Egypt
|
3
Department of Biochemistry, Institute of Chemistry, P.J. Šafárik University, Moyzesova 11, 041 54 Košice, Slovakia
|
4
Department of Biology and Ecology, Faculty of Science, University of Kragujevac, R. Domanovića 12, 34000 Kragujevac, Serbia.
|
5
Department of Biochemistry and Microbiology, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia.
|
6
NMR Laboratory, Institute of Chemistry, P.J. Šafárik University, Moyzesova 11, 041 54 Košice, Slovakia
|
Publication type: Journal Article
Publication date: 2017-02-01
Journal:
Journal of Inorganic Biochemistry
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 3.9
ISSN: 01620134, 18733344
Biochemistry
Inorganic Chemistry
Abstract
Starting from well-defined NH2(CH3)2[PdCl2(XQ)] complexes, coordination compounds of general formula Cat[PdCl2(XQ)] have been prepared by cationic exchange of NH2(CH3)2+ and Cat cations, where XQ are biologically active halogen derivatives of quinolin-8-ol (5-chloro-7-iodo-quinolin-8-ol (CQ), 5,7-dibromo-quinolin-8-ol (dBrQ) and 5,7-dichloro-quinolin-8-ol (dClQ)) and Cat is K+ or Cs+. The cation exchange of all prepared complexes, K[PdCl2(CQ)] (1), K[PdCl2(dClQ)] (2), K[PdCl2(dBrQ)] (3), Cs[PdCl2(CQ)] (4), Cs[PdCl2(dClQ)] (5) and Cs[PdCl2(dBrQ)] (6) was approved using IR spectroscopy, their structures in DMSO solution were elucidated by one- and two-dimensional NMR experiments, whereas their stability in solution was verified by UV-VIS spectroscopy. Interaction of complexes to ctDNA was investigated using UV-VIS and fluorescence emission spectroscopy. The minimum inhibitory concentration and the minimum microbicidal concentration values were detected against 15 bacterial strains and 4 yeast strains to examine the antimicrobial activity for the complexes. The in vitro antitumor properties of the complexes were studied by testing the complexes on leukemic cell line L1210, ovarian cancer cell line A2780 and non-cancerous cell line HEK293. The majority of the prepared compounds exhibited moderate antimicrobial and very high cytotoxic activity.
Top-30
Citations by journals
|
1
2
3
4
5
6
7
|
|
|
Polyhedron
7 publications, 36.84%
|
|
|
Inorganica Chimica Acta
2 publications, 10.53%
|
|
|
Journal of Molecular Structure
2 publications, 10.53%
|
|
|
Chemistry
1 publication, 5.26%
|
|
|
Transition Metal Chemistry
1 publication, 5.26%
|
|
|
Journal of Inorganic Biochemistry
1 publication, 5.26%
|
|
|
Coordination Chemistry Reviews
1 publication, 5.26%
|
|
|
Applied Organometallic Chemistry
1 publication, 5.26%
|
|
|
Russian Chemical Reviews
1 publication, 5.26%
|
|
|
Medicinal Chemistry
1 publication, 5.26%
|
|
|
1
2
3
4
5
6
7
|
Citations by publishers
|
2
4
6
8
10
12
14
|
|
|
Elsevier
13 publications, 68.42%
|
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 5.26%
|
|
|
Springer Nature
1 publication, 5.26%
|
|
|
Wiley
1 publication, 5.26%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 5.26%
|
|
|
Bentham Science
1 publication, 5.26%
|
|
|
2
4
6
8
10
12
14
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2017,2018,2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","",""],"datasets":[{"label":"Citations number","data":[3,2,4,2,2,1,4,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["15.79","10.53","21.05","10.53","10.53","5.26","21.05","5.26"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Polyhedron","Inorganica Chimica Acta","Journal of Molecular Structure","Chemistry","Transition Metal Chemistry","Journal of Inorganic Biochemistry","Coordination Chemistry Reviews","Applied Organometallic Chemistry","Russian Chemical Reviews","Medicinal Chemistry"],"ids":[21269,1406,9347,27005,4341,6830,13437,11683,23802,1917],"codes":[0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp"],"datasets":[{"label":"","data":[7,2,2,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[36.84,10.53,10.53,5.26,5.26,5.26,5.26,5.26,5.26,5.26],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","Springer Nature","Wiley","Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii","Bentham Science"],"ids":[17,202,8,11,9422,39],"codes":[0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp"],"datasets":[{"label":"","data":[13,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[68.42,5.26,5.26,5.26,5.26,5.26],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartiles":{"type":"bar","data":{"show":true,"labels":[2017,2018,2019,2020,2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,0,0,0,0,0],"percentage":["0","0","0","0","0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[0,0,0,0,0,0,1,0],"percentage":["0","0","0","0","0","0","5.26","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[3,2,2,2,2,1,1,1],"percentage":["15.79","10.53","10.53","10.53","10.53","5.26","5.26","5.26"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[0,0,1,0,0,0,2,0],"percentage":["0","0","5.26","0","0","0","10.53","0"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,1,0,0,0,0,0],"percentage":["0","0","5.26","0","0","0","0","0"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by SCImago per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartilesWs":{"type":"bar","data":{"show":true,"labels":[2017,2018,2019,2020,2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,0,0,0,0,0],"percentage":["0","0","0","0","0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[1,0,0,0,0,0,1,0],"percentage":["5.26","0","0","0","0","0","5.26","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[1,2,2,1,2,1,1,1],"percentage":["5.26","10.53","10.53","5.26","10.53","5.26","5.26","5.26"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[1,0,1,0,0,0,2,0],"percentage":["5.26","0","5.26","0","0","0","10.53","0"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,1,1,0,0,0,0],"percentage":["0","0","5.26","5.26","0","0","0","0"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by WoS per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Farkasova V. et al. Low-dimensional compounds containing bioactive ligands. Part VIII: DNA interaction, antimicrobial and antitumor activities of ionic 5,7-dihalo-8-quinolinolato palladium(II) complexes with K+ and Cs+ cations // Journal of Inorganic Biochemistry. 2017. Vol. 167. pp. 80-88.
GOST all authors (up to 50)
Copy
Farkasova V., Drweesh S. A., Lüköová A., Sabolová D., Radojevic I., Comic L., Vasić S. M., Paulikova H., Fečko S., Balašková T., Vilková M., Imrich J., Potočňák I. Low-dimensional compounds containing bioactive ligands. Part VIII: DNA interaction, antimicrobial and antitumor activities of ionic 5,7-dihalo-8-quinolinolato palladium(II) complexes with K+ and Cs+ cations // Journal of Inorganic Biochemistry. 2017. Vol. 167. pp. 80-88.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.jinorgbio.2016.11.021
UR - https://doi.org/10.1016/j.jinorgbio.2016.11.021
TI - Low-dimensional compounds containing bioactive ligands. Part VIII: DNA interaction, antimicrobial and antitumor activities of ionic 5,7-dihalo-8-quinolinolato palladium(II) complexes with K+ and Cs+ cations
T2 - Journal of Inorganic Biochemistry
AU - Farkasova, Veronika
AU - Drweesh, Sayed Ali
AU - Lüköová, Andrea
AU - Sabolová, Danica
AU - Radojevic, Ivana
AU - Comic, Ljiljana
AU - Vasić, Sava M
AU - Paulikova, Helena
AU - Fečko, Stanislav
AU - Balašková, Tatiana
AU - Vilková, Mária
AU - Imrich, Ján
AU - Potočňák, Ivan
PY - 2017
DA - 2017/02/01 00:00:00
PB - Elsevier
SP - 80-88
VL - 167
SN - 0162-0134
SN - 1873-3344
ER -
Cite this
BibTex
Copy
@article{2017_Farkasova,
author = {Veronika Farkasova and Sayed Ali Drweesh and Andrea Lüköová and Danica Sabolová and Ivana Radojevic and Ljiljana Comic and Sava M Vasić and Helena Paulikova and Stanislav Fečko and Tatiana Balašková and Mária Vilková and Ján Imrich and Ivan Potočňák},
title = {Low-dimensional compounds containing bioactive ligands. Part VIII: DNA interaction, antimicrobial and antitumor activities of ionic 5,7-dihalo-8-quinolinolato palladium(II) complexes with K+ and Cs+ cations},
journal = {Journal of Inorganic Biochemistry},
year = {2017},
volume = {167},
publisher = {Elsevier},
month = {feb},
url = {https://doi.org/10.1016/j.jinorgbio.2016.11.021},
pages = {80--88},
doi = {10.1016/j.jinorgbio.2016.11.021}
}