Recent progress in microchip electrophoresis–mass spectrometry
Тип публикации: Journal Article
Дата публикации: 2011-06-01
SCImago Q2
WOS Q2
БС1
SJR: 0.604
CiteScore: 6.5
Impact factor: 3.4
ISSN: 07317085, 1873264X
PubMed ID:
21130595
Drug Discovery
Spectroscopy
Pharmaceutical Science
Clinical Biochemistry
Analytical Chemistry
Краткое описание
This review highlights the methodological and instrumental developments in microchip electrophoresis (MCE)-mass spectrometry (MS) from 1997. In MCE-MS, the development of ionization interface is one of the most important issues to realize highly sensitive detection and high separation efficiency. Among several interfaces, electrospray ionization (ESI) has been mainly employed to MCE-MS since a simple structure of the ESI interface is suitable for coupling with the microchips. Although the number of publications is still limited, laser desorption ionization (LDI) interface has also been developed for MCE-MS. The characteristics of the ESI and LDI interfaces applied to the electrophoresis microchips are presented in this review. The scope of applications in MCE-MS covers mainly biogenic compounds such as bioactive amines, peptides, tryptic digests and proteins. This review provides a comprehensive table listing the applications in MCE-MS.
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ГОСТ
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Kitagawa F., Otsuka K. Recent progress in microchip electrophoresis–mass spectrometry // Journal of Pharmaceutical and Biomedical Analysis. 2011. Vol. 55. No. 4. pp. 668-678.
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Kitagawa F., Otsuka K. Recent progress in microchip electrophoresis–mass spectrometry // Journal of Pharmaceutical and Biomedical Analysis. 2011. Vol. 55. No. 4. pp. 668-678.
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TY - JOUR
DO - 10.1016/j.jpba.2010.11.013
UR - https://doi.org/10.1016/j.jpba.2010.11.013
TI - Recent progress in microchip electrophoresis–mass spectrometry
T2 - Journal of Pharmaceutical and Biomedical Analysis
AU - Kitagawa, Fumihiko
AU - Otsuka, Koji
PY - 2011
DA - 2011/06/01
PB - Elsevier
SP - 668-678
IS - 4
VL - 55
PMID - 21130595
SN - 0731-7085
SN - 1873-264X
ER -
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@article{2011_Kitagawa,
author = {Fumihiko Kitagawa and Koji Otsuka},
title = {Recent progress in microchip electrophoresis–mass spectrometry},
journal = {Journal of Pharmaceutical and Biomedical Analysis},
year = {2011},
volume = {55},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016/j.jpba.2010.11.013},
number = {4},
pages = {668--678},
doi = {10.1016/j.jpba.2010.11.013}
}
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MLA
Скопировать
Kitagawa, Fumihiko, and Koji Otsuka. “Recent progress in microchip electrophoresis–mass spectrometry.” Journal of Pharmaceutical and Biomedical Analysis, vol. 55, no. 4, Jun. 2011, pp. 668-678. https://doi.org/10.1016/j.jpba.2010.11.013.
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