A self-assembled fluorescent nanoprobe for detection of GSH and dual-channel imaging
Publication type: Journal Article
Publication date: 2018-03-01
scimago Q2
wos Q2
SJR: 0.694
CiteScore: 7.8
Impact factor: 4.7
ISSN: 10106030, 18732666
General Chemistry
General Chemical Engineering
General Physics and Astronomy
Abstract
We report a fluorescent nanoprobe based on the co-assembly of amphiphilic BODIPY and fluorescein for selective detection of GSH. The amphiphilic BODIPY derivative, consisting of hydrophobic BODIPY unit and hydrophilic PEG chains, co-assembled with fluorescein to give non-fluorescent nanoparticles due to the aggregation caused quenching. Upon addition of GSH, the thiol group of GSH reacted with BODIPY through nucleophilic substitution to afford highly polar GSH-substituted BODIPY with high solubility in water, resulting in the disassembly of the nanoparticles. The GSH-induced disassembly of the nanoparticles released the highly fluorescent BODIPY derivative and fluorescein, enabling the dual-emissive detection of GSH. This nanoprobe was applied for the dual-channel fluorescence imaging of GSH in living cells.
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Total citations:
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Citations from 2024:
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(31.25%)
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GOST
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Liu Y. et al. A self-assembled fluorescent nanoprobe for detection of GSH and dual-channel imaging // Journal of Photochemistry and Photobiology A: Chemistry. 2018. Vol. 355. pp. 311-317.
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Liu Y., Niu L., Chen Y., Yang Q. A self-assembled fluorescent nanoprobe for detection of GSH and dual-channel imaging // Journal of Photochemistry and Photobiology A: Chemistry. 2018. Vol. 355. pp. 311-317.
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RIS
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TY - JOUR
DO - 10.1016/j.jphotochem.2017.08.042
UR - https://doi.org/10.1016/j.jphotochem.2017.08.042
TI - A self-assembled fluorescent nanoprobe for detection of GSH and dual-channel imaging
T2 - Journal of Photochemistry and Photobiology A: Chemistry
AU - Liu, Yang
AU - Niu, Li-Ya
AU - Chen, Yuzhe
AU - Yang, Qingzheng
PY - 2018
DA - 2018/03/01
PB - Elsevier
SP - 311-317
VL - 355
SN - 1010-6030
SN - 1873-2666
ER -
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BibTex (up to 50 authors)
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@article{2018_Liu,
author = {Yang Liu and Li-Ya Niu and Yuzhe Chen and Qingzheng Yang},
title = {A self-assembled fluorescent nanoprobe for detection of GSH and dual-channel imaging},
journal = {Journal of Photochemistry and Photobiology A: Chemistry},
year = {2018},
volume = {355},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.jphotochem.2017.08.042},
pages = {311--317},
doi = {10.1016/j.jphotochem.2017.08.042}
}