Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties
E. B. Averina
2, 3
,
Nikolay A Zefirov
1
,
Birgit Wobith
4
,
Yuri Grishin
1
,
Olga N Zefirova
2, 3
,
Tamara S. Kuznetsova
1
,
Sergei Alexandrovich Kuznetsov
4
,
Nikolay S. Zefirov
2, 3
1
2
Publication type: Journal Article
Publication date: 2017-05-01
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
5-Aminoisoxazoles containing trimethoxy- and methylenedioxyphenyl moieties were prepared by heterocyclization of electrophilic alkenes with tetranitromethane in the presence of triethylamine with subsequent reduction of resulting 5-nitroisoxazoles. The crystal structure of 3,4,5-trimethoxybenzyl 5-aminoisoxazole-3-carboxylate was determined by X-ray analysis. Two novel 5-aminoisoxazoles demonstrated moderate antimitotic activity to human lung carcinoma A549 cell line.
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Total citations:
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Citations from 2025:
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(4.35%)
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GOST
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Vasilenko D. V. et al. Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties // Mendeleev Communications. 2017. Vol. 27. No. 3. pp. 228-230.
GOST all authors (up to 50)
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Vasilenko D. V., Averina E. B., Zefirov N. A., Wobith B., Grishin Y., Rybakov V. B., Zefirova O. N., Kuznetsova T. S., Kuznetsov S. A., Zefirov N. S. Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties // Mendeleev Communications. 2017. Vol. 27. No. 3. pp. 228-230.
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RIS
Copy
TY - JOUR
DO - 10.1016/j.mencom.2017.05.003
UR - https://doi.org/10.1016/j.mencom.2017.05.003
TI - Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties
T2 - Mendeleev Communications
AU - Vasilenko, Dmitry V.
AU - Averina, E. B.
AU - Zefirov, Nikolay A
AU - Wobith, Birgit
AU - Grishin, Yuri
AU - Rybakov, Victor B.
AU - Zefirova, Olga N
AU - Kuznetsova, Tamara S.
AU - Kuznetsov, Sergei Alexandrovich
AU - Zefirov, Nikolay S.
PY - 2017
DA - 2017/05/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 228-230
IS - 3
VL - 27
SN - 0959-9436
SN - 1364-551X
ER -
Cite this
BibTex (up to 50 authors)
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@article{2017_Vasilenko,
author = {Dmitry V. Vasilenko and E. B. Averina and Nikolay A Zefirov and Birgit Wobith and Yuri Grishin and Victor B. Rybakov and Olga N Zefirova and Tamara S. Kuznetsova and Sergei Alexandrovich Kuznetsov and Nikolay S. Zefirov},
title = {Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties},
journal = {Mendeleev Communications},
year = {2017},
volume = {27},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {may},
url = {https://doi.org/10.1016/j.mencom.2017.05.003},
number = {3},
pages = {228--230},
doi = {10.1016/j.mencom.2017.05.003}
}
Cite this
MLA
Copy
Vasilenko, Dmitry V., et al. “Synthesis and antimitotic activity of novel 5-aminoisoxazoles bearing alkoxyaryl moieties.” Mendeleev Communications, vol. 27, no. 3, May. 2017, pp. 228-230. https://doi.org/10.1016/j.mencom.2017.05.003.
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