Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators
Mstislav I. Lavrov
1, 2
,
Polina N Veremeeva
3
,
Dmitry S Karlov
1, 4
,
Vladimir L Zamoyski
5
,
Vladimir V. Grigoriev
1, 2
,
V. A. Palyulin
1, 2
1
3
Publication type: Journal Article
Publication date: 2019-11-22
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
Four new tricyclic derivatives of 3,7-diazabicyclo[3.3.1]-nonane (bispidine) have been synthesized. In vitro patch clamp investigation has revealed for one of them the positive modulation of the kainate-induced AMPA receptor currents in a nanomolar concentration range, and for two other compounds the corresponding negative modulation has been demonstrated.
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Total citations:
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Citations from 2025:
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(11.76%)
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GOST
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Lavrov M. I. et al. Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators // Mendeleev Communications. 2019. Vol. 29. No. 6. pp. 619-621.
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Lavrov M. I., Veremeeva P. N., Karlov D. S., Zamoyski V. L., Grigoriev V. V., Palyulin V. A. Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators // Mendeleev Communications. 2019. Vol. 29. No. 6. pp. 619-621.
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RIS
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TY - JOUR
DO - 10.1016/j.mencom.2019.11.004
UR - https://doi.org/10.1016/j.mencom.2019.11.004
TI - Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators
T2 - Mendeleev Communications
AU - Lavrov, Mstislav I.
AU - Veremeeva, Polina N
AU - Karlov, Dmitry S
AU - Zamoyski, Vladimir L
AU - Grigoriev, Vladimir V.
AU - Palyulin, V. A.
PY - 2019
DA - 2019/11/22
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 619-621
IS - 6
VL - 29
SN - 0959-9436
SN - 1364-551X
ER -
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BibTex (up to 50 authors)
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@article{2019_Lavrov,
author = {Mstislav I. Lavrov and Polina N Veremeeva and Dmitry S Karlov and Vladimir L Zamoyski and Vladimir V. Grigoriev and V. A. Palyulin},
title = {Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {nov},
url = {https://doi.org/10.1016/j.mencom.2019.11.004},
number = {6},
pages = {619--621},
doi = {10.1016/j.mencom.2019.11.004}
}
Cite this
MLA
Copy
Lavrov, Mstislav I., et al. “Tricyclic derivatives of bispidine as AMPA receptor allosteric modulators.” Mendeleev Communications, vol. 29, no. 6, Nov. 2019, pp. 619-621. https://doi.org/10.1016/j.mencom.2019.11.004.