A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells
Sergey A Gorbatov
1, 2
,
Denis Yu Uvarov
3
,
Igor V. Zavarzin
3
,
Yulia A Volkova
3
,
Anthony Romieu
1
Publication type: Journal Article
Publication date: 2020-11-01
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
The development of effective methods for real-time monitoring of nitroreductase (NTR) activity is of great significance for medical diagnosis and cancer research. Here, we present a novel water-soluble BODIPY-based chemodosimeter (NBB) for imaging the hypoxic status of human non-small-cell lung cancer A549 cells. We assume that ‘on–off’ response of NBB is activated by the NTRmediated reductive release of meso-phenol BODIPY dye resulting in unusual fluorescence.
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Gorbatov S. A. et al. A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells // Mendeleev Communications. 2020. Vol. 30. No. 6. pp. 750-752.
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Gorbatov S. A., Uvarov D. Yu., Scherbakov A. M., Zavarzin I. V., Volkova Y. A., Romieu A. A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells // Mendeleev Communications. 2020. Vol. 30. No. 6. pp. 750-752.
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TY - JOUR
DO - 10.1016/j.mencom.2020.11.020
UR - https://doi.org/10.1016/j.mencom.2020.11.020
TI - A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells
T2 - Mendeleev Communications
AU - Gorbatov, Sergey A
AU - Uvarov, Denis Yu
AU - Scherbakov, Alexander M.
AU - Zavarzin, Igor V.
AU - Volkova, Yulia A
AU - Romieu, Anthony
PY - 2020
DA - 2020/11/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 750-752
IS - 6
VL - 30
SN - 0959-9436
SN - 1364-551X
ER -
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BibTex (up to 50 authors)
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@article{2020_Gorbatov,
author = {Sergey A Gorbatov and Denis Yu Uvarov and Alexander M. Scherbakov and Igor V. Zavarzin and Yulia A Volkova and Anthony Romieu},
title = {A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {nov},
url = {https://doi.org/10.1016/j.mencom.2020.11.020},
number = {6},
pages = {750--752},
doi = {10.1016/j.mencom.2020.11.020}
}
Cite this
MLA
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Gorbatov, Sergey A., et al. “A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells.” Mendeleev Communications, vol. 30, no. 6, Nov. 2020, pp. 750-752. https://doi.org/10.1016/j.mencom.2020.11.020.