volume 31 issue 2 pages 210-212

Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity

Publication typeJournal Article
Publication date2021-03-31
scimago Q3
wos Q3
SJR0.305
CiteScore3.0
Impact factor1.7
ISSN09599436, 1364551X
General Chemistry
Abstract
The Buchwald–Hartwig cross-coupling of 5-bromo-4-(furan-2-yl)pyrimidine with various anilines afforded the corresponding new 5-(arylamino)pyrimidines, the reaction being accelerated by microwave irradiation. Most of the obtained compounds proved to possess a high bacteriostatic in vitro effect against Mycobacterium tuberculosis H37Rv, Neisseria gonorrhoeae, and Staphylococcus aureus including Methicillin-resistant strain, which is stronger than that of the commercial drug Spectinomycin.
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GOST Copy
Verbitskiy E. V. et al. Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity // Mendeleev Communications. 2021. Vol. 31. No. 2. pp. 210-212.
GOST all authors (up to 50) Copy
Verbitskiy E. V., Baskakova S. A., Belyaev D. V., Vakhrusheva D. V., Eremeeva N. I., Rusinov G. L., Charushin V. Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity // Mendeleev Communications. 2021. Vol. 31. No. 2. pp. 210-212.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2021.03.021
UR - https://doi.org/10.1016/j.mencom.2021.03.021
TI - Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity
T2 - Mendeleev Communications
AU - Verbitskiy, Egor V.
AU - Baskakova, Svetlana A
AU - Belyaev, Danila V
AU - Vakhrusheva, Diana V.
AU - Eremeeva, Natalya I.
AU - Rusinov, Gennady L.
AU - Charushin, Valery
PY - 2021
DA - 2021/03/31
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 210-212
IS - 2
VL - 31
SN - 0959-9436
SN - 1364-551X
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Verbitskiy,
author = {Egor V. Verbitskiy and Svetlana A Baskakova and Danila V Belyaev and Diana V. Vakhrusheva and Natalya I. Eremeeva and Gennady L. Rusinov and Valery Charushin},
title = {Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity},
journal = {Mendeleev Communications},
year = {2021},
volume = {31},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {mar},
url = {https://doi.org/10.1016/j.mencom.2021.03.021},
number = {2},
pages = {210--212},
doi = {10.1016/j.mencom.2021.03.021}
}
MLA
Cite this
MLA Copy
Verbitskiy, Egor V., et al. “Renaissance of 4-(5-nitrofuran-2-yl)-5-arylamino substituted pyrimidines: microwave-assisted synthesis and antitubercular activity.” Mendeleev Communications, vol. 31, no. 2, Mar. 2021, pp. 210-212. https://doi.org/10.1016/j.mencom.2021.03.021.