Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones
Victor A Egorov
1
,
Lidiya S Khasanova
1
,
Fanuza A Gimalova
1
,
Diana V Ishmetova
2
,
Vener A. Vakhitov
2
,
Mansur S Miftakhov
1
Publication type: Journal Article
Publication date: 2022-03-31
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
Novel 2,4-dichloro-5-phenylcyclopent-4-ene-1,3-dione and 5-aryl-4-chlorocyclopent-4-ene-1,3-dione were synthesized by the Suzuki–Miyaura or Friedel–Crafts reactions of the di- and trichlorocyclopentenone monoketals and subsequent hydrolysis of the ketal function. Condensation of these diones with (hetero)aromatic aldehydes afforded multifunctional 1,3-cyclopentenediones that showed anticancer activity.Keywords : organochlorine compounds, cyclopentenones, ketals, Suzuki–Miyaura reaction, Friedel–Crafts reaction, Knoevenagel condensation, aldehydes, cross-conjugated cyclopentene-1,3-diones, cytotoxicity.
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Egorov V. A. et al. Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 183-185.
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Egorov V. A., Khasanova L. S., Gimalova F. A., Lobov A. N., Ishmetova D. V., Vakhitov V. A., Miftakhov M. S. Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 183-185.
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RIS
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TY - JOUR
DO - 10.1016/j.mencom.2022.03.010
UR - https://doi.org/10.1016/j.mencom.2022.03.010
TI - Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones
T2 - Mendeleev Communications
AU - Egorov, Victor A
AU - Khasanova, Lidiya S
AU - Gimalova, Fanuza A
AU - Lobov, Alexander Nikolaevich
AU - Ishmetova, Diana V
AU - Vakhitov, Vener A.
AU - Miftakhov, Mansur S
PY - 2022
DA - 2022/03/31
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 183-185
IS - 2
VL - 32
SN - 0959-9436
SN - 1364-551X
ER -
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@article{2022_Egorov,
author = {Victor A Egorov and Lidiya S Khasanova and Fanuza A Gimalova and Alexander Nikolaevich Lobov and Diana V Ishmetova and Vener A. Vakhitov and Mansur S Miftakhov},
title = {Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {mar},
url = {https://doi.org/10.1016/j.mencom.2022.03.010},
number = {2},
pages = {183--185},
doi = {10.1016/j.mencom.2022.03.010}
}
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MLA
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Egorov, Victor A., et al. “Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones.” Mendeleev Communications, vol. 32, no. 2, Mar. 2022, pp. 183-185. https://doi.org/10.1016/j.mencom.2022.03.010.
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