volume 32 issue 2 pages 183-185

Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones

Publication typeJournal Article
Publication date2022-03-31
scimago Q3
wos Q3
SJR0.305
CiteScore3.0
Impact factor1.7
ISSN09599436, 1364551X
General Chemistry
Abstract
Novel 2,4-dichloro-5-phenylcyclopent-4-ene-1,3-dione and 5-aryl-4-chlorocyclopent-4-ene-1,3-dione were synthesized by the Suzuki–Miyaura or Friedel–Crafts reactions of the di- and trichlorocyclopentenone monoketals and subsequent hydrolysis of the ketal function. Condensation of these diones with (hetero)aromatic aldehydes afforded multifunctional 1,3-cyclopentenediones that showed anticancer activity.Keywords : organochlorine compounds, cyclopentenones, ketals, Suzuki–Miyaura reaction, Friedel–Crafts reaction, Knoevenagel condensation, aldehydes, cross-conjugated cyclopentene-1,3-diones, cytotoxicity.
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Egorov V. A. et al. Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 183-185.
GOST all authors (up to 50) Copy
Egorov V. A., Khasanova L. S., Gimalova F. A., Lobov A. N., Ishmetova D. V., Vakhitov V. A., Miftakhov M. S. Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 183-185.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2022.03.010
UR - https://doi.org/10.1016/j.mencom.2022.03.010
TI - Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones
T2 - Mendeleev Communications
AU - Egorov, Victor A
AU - Khasanova, Lidiya S
AU - Gimalova, Fanuza A
AU - Lobov, Alexander Nikolaevich
AU - Ishmetova, Diana V
AU - Vakhitov, Vener A.
AU - Miftakhov, Mansur S
PY - 2022
DA - 2022/03/31
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 183-185
IS - 2
VL - 32
SN - 0959-9436
SN - 1364-551X
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2022_Egorov,
author = {Victor A Egorov and Lidiya S Khasanova and Fanuza A Gimalova and Alexander Nikolaevich Lobov and Diana V Ishmetova and Vener A. Vakhitov and Mansur S Miftakhov},
title = {Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {mar},
url = {https://doi.org/10.1016/j.mencom.2022.03.010},
number = {2},
pages = {183--185},
doi = {10.1016/j.mencom.2022.03.010}
}
MLA
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MLA Copy
Egorov, Victor A., et al. “Cytotoxicity of novel cross-conjugated arylated cyclopentene-1,3-diones.” Mendeleev Communications, vol. 32, no. 2, Mar. 2022, pp. 183-185. https://doi.org/10.1016/j.mencom.2022.03.010.