Noncatalytic on water aldol reaction of isatins with cyclic 1,3-diketones at room temperature without the need for subsequent chromatography
Publication type: Journal Article
Publication date: 2022-07-01
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
Noncatalytic on water aldol transformation of isatins and cyclic 1,3-diketones results in substituted 3-hydroxy-3-(2-hydroxy-6-oxocyclohex-1-en-1-yl)indolin-2-ones in 87–98% yields. Optimized conditions have been found and a mechanistic rationale for the reaction has been deduced. The new efficient and facile process represents a convenient way to compounds with the 3-hydroxyindolin-2-one and 3-hydroxycyclohex-2-en-1-one moieties.
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Elinson M. N. et al. Noncatalytic on water aldol reaction of isatins with cyclic 1,3-diketones at room temperature without the need for subsequent chromatography // Mendeleev Communications. 2022. Vol. 32. No. 4. pp. 543-545.
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Elinson M. N., Ryzhkova Y. E., Kalashnikova V. M., Egorov M. P. Noncatalytic on water aldol reaction of isatins with cyclic 1,3-diketones at room temperature without the need for subsequent chromatography // Mendeleev Communications. 2022. Vol. 32. No. 4. pp. 543-545.
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TY - JOUR
DO - 10.1016/j.mencom.2022.07.036
UR - https://doi.org/10.1016/j.mencom.2022.07.036
TI - Noncatalytic on water aldol reaction of isatins with cyclic 1,3-diketones at room temperature without the need for subsequent chromatography
T2 - Mendeleev Communications
AU - Elinson, M. N.
AU - Ryzhkova, Yuliya E.
AU - Kalashnikova, Varvara M
AU - Egorov, M. P.
PY - 2022
DA - 2022/07/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 543-545
IS - 4
VL - 32
SN - 0959-9436
SN - 1364-551X
ER -
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@article{2022_Elinson,
author = {M. N. Elinson and Yuliya E. Ryzhkova and Varvara M Kalashnikova and M. P. Egorov},
title = {Noncatalytic on water aldol reaction of isatins with cyclic 1,3-diketones at room temperature without the need for subsequent chromatography},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {jul},
url = {https://doi.org/10.1016/j.mencom.2022.07.036},
number = {4},
pages = {543--545},
doi = {10.1016/j.mencom.2022.07.036}
}
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Elinson, M. N., et al. “Noncatalytic on water aldol reaction of isatins with cyclic 1,3-diketones at room temperature without the need for subsequent chromatography.” Mendeleev Communications, vol. 32, no. 4, Jul. 2022, pp. 543-545. https://doi.org/10.1016/j.mencom.2022.07.036.