Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units
Тип публикации: Journal Article
Дата публикации: 2022-09-01
scimago Q3
wos Q3
БС1
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Краткое описание
A three-component tandem protocol involving the reactions of bis(benzohydrazides), aromatic aldehydes and chloramine trihydrate yielded a new series of bis(1,3,4-oxadiazoles). The target hybrids were formed by an initial bis( N -benzoyl-hydrazones) formation, followed by chloramine trihydrate- mediated oxidative cyclization. The 4-methoxyphenyl-containing compounds demonstrated promising antibacterial activity against the Staphylococcus aureus and Pseudomonas aeruginosa strains with MIC value of 1.6 µm.
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Mekky A. E., Sanad S. M. H., Abdelfattah A. Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units // Mendeleev Communications. 2022. Vol. 32. No. 5. pp. 612-614.
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Mekky A. E., Sanad S. M. H., Abdelfattah A. Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units // Mendeleev Communications. 2022. Vol. 32. No. 5. pp. 612-614.
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TY - JOUR
DO - 10.1016/j.mencom.2022.09.014
UR - https://doi.org/10.1016/j.mencom.2022.09.014
TI - Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units
T2 - Mendeleev Communications
AU - Mekky, Ahmed E
AU - Sanad, Sherif M H
AU - Abdelfattah, Ahmed
PY - 2022
DA - 2022/09/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 612-614
IS - 5
VL - 32
SN - 0959-9436
SN - 1364-551X
ER -
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@article{2022_Mekky,
author = {Ahmed E Mekky and Sherif M H Sanad and Ahmed Abdelfattah},
title = {Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {sep},
url = {https://doi.org/10.1016/j.mencom.2022.09.014},
number = {5},
pages = {612--614},
doi = {10.1016/j.mencom.2022.09.014}
}
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Mekky, Ahmed E., et al. “Tandem synthesis, antibacterial evaluation and SwissADME prediction study of new bis(1,3,4-oxadiazoles) linked to arene units.” Mendeleev Communications, vol. 32, no. 5, Sep. 2022, pp. 612-614. https://doi.org/10.1016/j.mencom.2022.09.014.