New regio/chemoselective synthesis of hydrogenated imidazo[1,5-b]pyridazines
Publication type: Journal Article
Publication date: 2022-09-01
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
The cascade heterocyclization of 1,2-diamino-4-phenyl-imidazole with ethyl 2-arylidene-2-cyanoacetates affords 1,2,3,4-tetrahydroimidazo[1,5- b ]pyridazine-3-carbonitrile derivatives as mixtures of diastereomers. The experimental data and quantum chemical calculations were used to propose processes. The three-component processing with above-mentioned diamine, ethyl cyanoacetate and aromatic aldehydes leads to the same products in generally lower yields.
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Vandyshev D. Yu. et al. New regio/chemoselective synthesis of hydrogenated imidazo[1,5-b]pyridazines // Mendeleev Communications. 2022. Vol. 32. No. 5. pp. 637-639.
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Vandyshev D. Yu., Shikhaliev K. S., Krysin M. Yu., Ilyinova T. N., Mangusheva D. A., Sidorenko O. E., Iminova R. R. New regio/chemoselective synthesis of hydrogenated imidazo[1,5-b]pyridazines // Mendeleev Communications. 2022. Vol. 32. No. 5. pp. 637-639.
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TY - JOUR
DO - 10.1016/j.mencom.2022.09.023
UR - https://doi.org/10.1016/j.mencom.2022.09.023
TI - New regio/chemoselective synthesis of hydrogenated imidazo[1,5-b]pyridazines
T2 - Mendeleev Communications
AU - Vandyshev, Dmitry Yu
AU - Shikhaliev, Khidmet S
AU - Krysin, Michael Yu
AU - Ilyinova, Tatiana N
AU - Mangusheva, Daria A
AU - Sidorenko, Oleg E
AU - Iminova, Renata R
PY - 2022
DA - 2022/09/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 637-639
IS - 5
VL - 32
SN - 0959-9436
SN - 1364-551X
ER -
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@article{2022_Vandyshev,
author = {Dmitry Yu Vandyshev and Khidmet S Shikhaliev and Michael Yu Krysin and Tatiana N Ilyinova and Daria A Mangusheva and Oleg E Sidorenko and Renata R Iminova},
title = {New regio/chemoselective synthesis of hydrogenated imidazo[1,5-b]pyridazines},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {sep},
url = {https://doi.org/10.1016/j.mencom.2022.09.023},
number = {5},
pages = {637--639},
doi = {10.1016/j.mencom.2022.09.023}
}
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MLA
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Vandyshev, Dmitry Yu., et al. “New regio/chemoselective synthesis of hydrogenated imidazo[1,5-b]pyridazines.” Mendeleev Communications, vol. 32, no. 5, Sep. 2022, pp. 637-639. https://doi.org/10.1016/j.mencom.2022.09.023.