Mendeleev Communications

, том 32 , издание 6 , страницы 745-746

Optimized method for the recombinant production of a sea anemone’s peptide

Mikhail N. Tereshin ^{1, 2}

Alina M. Komyakova ¹

Vasily N Stepanenko ¹

Igor V Myagkikh ¹

Natalia S Shoshina ¹

Yuliya V. Korolkova ¹

E. V. Leychenko ^{3, 4}

Sergey A. Kozlov ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 4 аффилиации

M. M. Shemyakin–Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russian Federation |

M. V. Lomonosov Institute of Fine Chemical Technologies, MIREA – Russian Technological University, 119454 Moscow, Russian Federation |

Advanced Engineering School ‘Institute of Biotechnology, Bioengineering and Food Systems’, Far Eastern Federal University, 690922 Vladivostok, Russian Federation |

⁴

G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russian Federation |

Тип публикации: Journal Article

Дата публикации: 2022-11-28

OOO Zhurnal "Mendeleevskie Soobshcheniya"

Mendeleev Communications

scimago Q3

wos Q3

БС1

SJR: 0.305

CiteScore: 3.0

Impact factor: 1.7

ISSN: 09599436, 1364551X

DOI: 10.1016/j.mencom.2022.11.012

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General Chemistry

Краткое описание

The production of the analgesic peptide HCRG21 for medical use is restricted by a number of limitations in the technology. The optimal biotechnological method scalable to industrial has been developed based on the production of a fusion protein containing a special leader, His-tag, and Smt3 sequence upstream in the peptide sequence. The resulting peptide shared its inhibitory activity to TRPV1 ion channel identical to the published early.

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International Journal of Molecular Sciences	International Journal of Molecular Sciences, 1, 50% International Journal of Molecular Sciences 1 публикация, 50%
Mendeleev Communications	Mendeleev Communications, 1, 50% Mendeleev Communications 1 публикация, 50%
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Tereshin M. N. et al. Optimized method for the recombinant production of a sea anemone’s peptide // Mendeleev Communications. 2022. Vol. 32. No. 6. pp. 745-746.

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Tereshin M. N., Komyakova A. M., Stepanenko V. N., Myagkikh I. V., Shoshina N. S., Korolkova Y. V., Leychenko E. V., Kozlov S. A. Optimized method for the recombinant production of a sea anemone’s peptide // Mendeleev Communications. 2022. Vol. 32. No. 6. pp. 745-746.

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TY - JOUR

DO - 10.1016/j.mencom.2022.11.012

UR - https://doi.org/10.1016/j.mencom.2022.11.012

TI - Optimized method for the recombinant production of a sea anemone’s peptide

T2 - Mendeleev Communications

AU - Tereshin, Mikhail N.

AU - Komyakova, Alina M.

AU - Stepanenko, Vasily N

AU - Myagkikh, Igor V

AU - Shoshina, Natalia S

AU - Korolkova, Yuliya V.

AU - Leychenko, E. V.

AU - Kozlov, Sergey A.

PY - 2022

DA - 2022/11/28

PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"

SP - 745-746

IS - 6

VL - 32

SN - 0959-9436

SN - 1364-551X

ER -

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@article{2022_Tereshin,

author = {Mikhail N. Tereshin and Alina M. Komyakova and Vasily N Stepanenko and Igor V Myagkikh and Natalia S Shoshina and Yuliya V. Korolkova and E. V. Leychenko and Sergey A. Kozlov},

title = {Optimized method for the recombinant production of a sea anemone’s peptide},

journal = {Mendeleev Communications},

year = {2022},

volume = {32},

publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},

month = {nov},

url = {https://doi.org/10.1016/j.mencom.2022.11.012},

number = {6},

pages = {745--746},

doi = {10.1016/j.mencom.2022.11.012}

}

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Tereshin, Mikhail N., et al. “Optimized method for the recombinant production of a sea anemone’s peptide.” Mendeleev Communications, vol. 32, no. 6, Nov. 2022, pp. 745-746. https://doi.org/10.1016/j.mencom.2022.11.012.