Mendeleev Communications
,  volume 33 ,  issue 1 ,  pages 70-72

New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system

Elena A Golubeva 1
, 
Mstislav I. Lavrov 1
, 
Polina N Veremeeva 1
, 
Evgenia M Bovina 1
, 
Eugene V. Radchenko 1
, 
Maxim A Topchiy 2
, 
Andrey Asachenko 2
, 
Vladimir L Zamoyski 3
, 
Vladimir Viktorovich Grigoriev 1, 3
, 
Vladimir A. Palyulin 1
1
 
2
 
3
 
Publication type: Journal Article
Publication date: 2023-01-01
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
An optimized synthesis of N-{5-[(1,11-dimethyl-4,8,12-trioxo-3,6,9-triazatricyclo[7.3.1.13,11]tetradec-6-yl)methyl]-indan-2-yl}-1,3-benzodioxole-5-carboxamide has been carried out from indan-2-one oxime in seven steps. In vitro studies using electrophysiological patch clamp technique have revealed a positive modulation effect of this compound on kainate induced currents in Purkinje neurons in a wide range of concentrations from 10–12 to 10–8 m.
Found 
Found 

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Golubeva E. A. et al. New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system // Mendeleev Communications. 2023. Vol. 33. No. 1. pp. 70-72.
GOST all authors (up to 50) Copy
Golubeva E. A., Lavrov M. I., Veremeeva P. N., Bovina E. M., Radchenko E. V., Topchiy M. A., Asachenko A., Zamoyski V. L., Grigoriev V. V., Palyulin V. A. New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system // Mendeleev Communications. 2023. Vol. 33. No. 1. pp. 70-72.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2023.01.022
UR - https://doi.org/10.1016/j.mencom.2023.01.022
TI - New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system
T2 - Mendeleev Communications
AU - Golubeva, Elena A
AU - Lavrov, Mstislav I.
AU - Veremeeva, Polina N
AU - Bovina, Evgenia M
AU - Radchenko, Eugene V.
AU - Topchiy, Maxim A
AU - Asachenko, Andrey
AU - Zamoyski, Vladimir L
AU - Grigoriev, Vladimir Viktorovich
AU - Palyulin, Vladimir A.
PY - 2023
DA - 2023/01/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 70-72
IS - 1
VL - 33
SN - 0959-9436
SN - 1364-551X
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Golubeva,
author = {Elena A Golubeva and Mstislav I. Lavrov and Polina N Veremeeva and Evgenia M Bovina and Eugene V. Radchenko and Maxim A Topchiy and Andrey Asachenko and Vladimir L Zamoyski and Vladimir Viktorovich Grigoriev and Vladimir A. Palyulin},
title = {New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {jan},
url = {https://doi.org/10.1016/j.mencom.2023.01.022},
number = {1},
pages = {70--72},
doi = {10.1016/j.mencom.2023.01.022}
}
MLA
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MLA Copy
Golubeva, Elena A., et al. “New 1,11-dimethyl-3,6,9-triazatricyclo[7.3.1.13,11]tetradecane-4,8,12-trione derivative as an allosteric modulator of the glutamatergic system.” Mendeleev Communications, vol. 33, no. 1, Jan. 2023, pp. 70-72. https://doi.org/10.1016/j.mencom.2023.01.022.