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Journal of Molecular Liquids, volume 327, pages 114806

Novel lactide derivatives of p-tert-butylthiacalix[4]arene: Directed synthesis and molecular recognition of catecholamines

Publication typeJournal Article
Publication date2021-04-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor6
ISSN01677322, 18733166
Materials Chemistry
Electronic, Optical and Magnetic Materials
Physical and Theoretical Chemistry
Spectroscopy
Atomic and Molecular Physics, and Optics
Condensed Matter Physics
Abstract
Three stereoisomeric forms of p-tert-butylthiacalix[4]arene (cone, partial cone, and 1,3-alternate conformations) have been proposed as macrocyclic scaffold to obtain dendrimer-like compounds. Modification of the macrocycle with fragments containing both amide and lactide groups made it possible to obtain original analogs of dendrimers with symmetric and asymmetric structures. These compounds are capable of binding catecholamines (dopamine, epinephrine, and norepinephrine). The influence of the macrocyclic platform conformation of the compounds obtained on the efficiency and selectivity of their complexation with catecholamines was established by UV–visible, fluorescence and NMR spectroscopy. It was found that the 1,3-alternate conformation of the macrocycle core was the most favorable for binding all the guests. In case of the cone conformation, selectivity of binding of epinephrine and norepinephrine was observed. Location of catecholamines in the resulting complexes against the macrocyclic platform affected the efficiency of interaction of the synthesized thiacalixarenes with guests.

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GOST Copy
Mostovaya O. A. et al. Novel lactide derivatives of p-tert-butylthiacalix[4]arene: Directed synthesis and molecular recognition of catecholamines // Journal of Molecular Liquids. 2021. Vol. 327. p. 114806.
GOST all authors (up to 50) Copy
Mostovaya O. A., Padnya P. L., Shurpik D. N., Shiabiev I. E., Stoikov I. I., Padnya P., Shurpik D. N., Stoikov I. Novel lactide derivatives of p-tert-butylthiacalix[4]arene: Directed synthesis and molecular recognition of catecholamines // Journal of Molecular Liquids. 2021. Vol. 327. p. 114806.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.molliq.2020.114806
UR - https://doi.org/10.1016/j.molliq.2020.114806
TI - Novel lactide derivatives of p-tert-butylthiacalix[4]arene: Directed synthesis and molecular recognition of catecholamines
T2 - Journal of Molecular Liquids
AU - Mostovaya, O A
AU - Padnya, P L
AU - Shurpik, D N
AU - Shiabiev, I E
AU - Stoikov, I I
AU - Padnya, Pavel
AU - Shurpik, Dmitriy N
AU - Stoikov, Ivan
PY - 2021
DA - 2021/04/01 00:00:00
PB - Elsevier
SP - 114806
VL - 327
SN - 0167-7322
SN - 1873-3166
ER -
BibTex
Cite this
BibTex Copy
@article{2021_Mostovaya,
author = {O A Mostovaya and P L Padnya and D N Shurpik and I E Shiabiev and I I Stoikov and Pavel Padnya and Dmitriy N Shurpik and Ivan Stoikov},
title = {Novel lactide derivatives of p-tert-butylthiacalix[4]arene: Directed synthesis and molecular recognition of catecholamines},
journal = {Journal of Molecular Liquids},
year = {2021},
volume = {327},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/j.molliq.2020.114806},
pages = {114806},
doi = {10.1016/j.molliq.2020.114806}
}
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