Materials Science and Engineering C, volume 33, issue 5, pages 3047-3053
Preparation of N,O-carboxymethyl chitosan coated alginate microcapsules and their application to Bifidobacterium longum BIOMA 5920
Publication type: Journal Article
Publication date: 2013-07-01
Journal:
Materials Science and Engineering C
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 7.9
ISSN: 09284931, 18730191
Bioengineering
Biomaterials
Mechanics of Materials
Abstract
In order to greatly improve vitality of probiotic bacteria within the application, a novel biocompatible vehicle, N,O-carboxymethyl chitosan (NOCs) with appropriate degrees of substitution coat alginate (ALg) microparticles, was prepared by electrostatic droplet generation. The amount of chitosan (Cs) and N,O-carboxymethyl chitosan (NOCs) coated on the ALg microparticles was determined by differential scanning calorimetry. The surface morphology of ALg microparticles, Cs coated ALg microparticles and NOCs coated ALg microparticles was determined using scanning electron microscopy. The coating thickness of Cs coated ALg microparticles and that of NOCs coated ALg microparticles was directly observed with confocal laser scanning microscopy. In order to assess pH sensitivity of microparticles, the bovine serum albumin release from the microspheres was tested in acid solution (pH 2.0) for 2 h and subsequently in alkaline solution (pH 7.0) for 2 h. The survival of Bifidobacterium longum BIOMA 5920 loaded in NOCs coated with ALg microparticle was improved in simulated gastric juice (pH 2.0, for 2 h) compared to that of B. longum BIOMA 5920 loaded in ALg microparticles and Cs coated ALg microparticles. After incubation in simulated intestinal juices (pH 7.0, 2 h), the release of microencapsulated B. longum BIOMA 5920 was investigated.
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Citations by publishers
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1 publication, 4.35%
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1 publication, 4.35%
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Mi Yu. et al. Preparation of N,O-carboxymethyl chitosan coated alginate microcapsules and their application to Bifidobacterium longum BIOMA 5920 // Materials Science and Engineering C. 2013. Vol. 33. No. 5. pp. 3047-3053.
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Mi Yu., Su R., Fan D., Xiaoli Zhu X. Z., Zhang W. N. Preparation of N,O-carboxymethyl chitosan coated alginate microcapsules and their application to Bifidobacterium longum BIOMA 5920 // Materials Science and Engineering C. 2013. Vol. 33. No. 5. pp. 3047-3053.
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TY - JOUR
DO - 10.1016/j.msec.2013.03.035
UR - https://doi.org/10.1016/j.msec.2013.03.035
TI - Preparation of N,O-carboxymethyl chitosan coated alginate microcapsules and their application to Bifidobacterium longum BIOMA 5920
T2 - Materials Science and Engineering C
AU - Mi, Yu
AU - Su, Ran
AU - Fan, Daidi
AU - Xiaoli Zhu, Xiaoli Zhu
AU - Zhang, Wen Ni
PY - 2013
DA - 2013/07/01 00:00:00
PB - Elsevier
SP - 3047-3053
IS - 5
VL - 33
SN - 0928-4931
SN - 1873-0191
ER -
Cite this
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@article{2013_Mi,
author = {Yu Mi and Ran Su and Daidi Fan and Xiaoli Zhu Xiaoli Zhu and Wen Ni Zhang},
title = {Preparation of N,O-carboxymethyl chitosan coated alginate microcapsules and their application to Bifidobacterium longum BIOMA 5920},
journal = {Materials Science and Engineering C},
year = {2013},
volume = {33},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.msec.2013.03.035},
number = {5},
pages = {3047--3053},
doi = {10.1016/j.msec.2013.03.035}
}
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MLA
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Mi, Yu., et al. “Preparation of N,O-carboxymethyl chitosan coated alginate microcapsules and their application to Bifidobacterium longum BIOMA 5920.” Materials Science and Engineering C, vol. 33, no. 5, Jul. 2013, pp. 3047-3053. https://doi.org/10.1016/j.msec.2013.03.035.