Open Access

Microvascular Research, volume 144, pages 104419

Skin microcirculation in middle-aged men with newly diagnosed arterial hypertension according to remote laser Doppler flowmetry data

Fedorovich Andrey A. ^{1, 2}

Loktionova Yulia I. ³

Zharkikh Elena V. ^{3, 4}

Gorshkov Alexander Y. ²

Korolev A.I. ²

Dadaeva Valida Arslanalievna ²

Drapkina Oxana M ²

Zherebtsov Evgeny A. ⁴

Hide authors affiliations Show authors affiliations: 4 affiliations

FSBI SRC RF “Institute of Biomedical Problems” RAS, Moscow, Russia |

FSBI “National Health and Research Center of Preventive Healthcare” of the Ministry of Health of Russia, Moscow, Russia |

Research & Development Center of Biomedical Photonics, Orel State University, Orel, Russia |

⁴

Optoelectronics and Measurement Techniques, University of Oulu, Oulu, Finland |

Publication type: Journal Article

Publication date: 2022-11-01

Elsevier

Journal: Microvascular Research

Quartile SCImago

Quartile WOS

Impact factor: 3.1

ISSN: 00262862, 10959319

DOI: 10.1016/j.mvr.2022.104419

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Biochemistry

Cell Biology

Cardiology and Cardiovascular Medicine

Abstract

This work aims to study the functional state of resistive skin microvessels in patients with newly diagnosed arterial hypertension (AH), using portable laser Doppler flowmetry (LDF) devices. The study included 89 men aged 30 to 60 years (44.4 ± 8.5) who had no known medical complaints, subjectively considered themselves healthy, and did not take medications on a regular basis. All the men underwent LDF on the left forearm, daily blood pressure (BP) monitoring (DBPM) on the left arm, echocardiography, and laboratory tests. According to DBPM data, the men were divided into two groups. The control group (CG) consisted of 30 men with normal BP, and 59 men were included in the AH group. According to LDF data, in men with AH, there is a decrease in the amplitude (tone increase) of neurogenic and myogenic vasomotion, a decrease in the amplitude of pulse oscillations of microcirculatory flow, a decrease in perfusion efficiency of endothelial, neurogenic, myogenic and pulse mechanisms of tissue perfusion regulation. Of all tone-forming mechanisms, only the myogenic mechanism has a weak negative correlation with systolic blood pressure level. The amplitude of pulse oscillations demonstrates the highest degree of correlation with blood pressure parameters. The functional disorders of vasomotor activity of resistive skin microvessels revealed in men with AH have minor correlations with the level of blood pressure. Despite this, the use of portable devices for remote LDF may be a useful method for the dynamic monitoring of patients with hypertension, which requires further research. • In early arterial hypertension (AH) perfusion efficiency in skin is reduced. • Neurogenic and myogenic vasomotor tones increase with the development of AH. • Pulse oscillations demonstrate the highest correlation with blood pressure. • Wrist-mounted LDF monitors are promising for early hypertension monitoring.

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Citations by journals

	1
Diagnostics	Diagnostics, 1, 14.29% Diagnostics 1 publication, 14.29%
Pathophysiology	Pathophysiology, 1, 14.29% Pathophysiology 1 publication, 14.29%
Journal of Biophotonics	Journal of Biophotonics, 1, 14.29% Journal of Biophotonics 1 publication, 14.29%
IEEE Transactions on Biomedical Engineering	IEEE Transactions on Biomedical Engineering, 1, 14.29% IEEE Transactions on Biomedical Engineering 1 publication, 14.29%
Microvascular Research	Microvascular Research, 1, 14.29% Microvascular Research 1 publication, 14.29%
Journal of Science in Sport and Exercise	Journal of Science in Sport and Exercise, 1, 14.29% Journal of Science in Sport and Exercise 1 publication, 14.29%
	1

Citations by publishers

	1 2
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 2, 28.57% Multidisciplinary Digital Publishing Institute (MDPI) 2 publications, 28.57%
Wiley	Wiley, 1, 14.29% Wiley 1 publication, 14.29%
IEEE	IEEE, 1, 14.29% IEEE 1 publication, 14.29%
Elsevier	Elsevier, 1, 14.29% Elsevier 1 publication, 14.29%
Springer Nature	Springer Nature, 1, 14.29% Springer Nature 1 publication, 14.29%
	1 2

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Fedorovich A. A. et al. Skin microcirculation in middle-aged men with newly diagnosed arterial hypertension according to remote laser Doppler flowmetry data // Microvascular Research. 2022. Vol. 144. p. 104419.

GOST all authors (up to 50) Copy

Fedorovich A. A., Loktionova Y. I., Zharkikh E. V., Gorshkov A. Y., Korolev A., Dadaeva V. A., Drapkina O. M., Zherebtsov E. A. Skin microcirculation in middle-aged men with newly diagnosed arterial hypertension according to remote laser Doppler flowmetry data // Microvascular Research. 2022. Vol. 144. p. 104419.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.mvr.2022.104419

UR - https://doi.org/10.1016%2Fj.mvr.2022.104419

TI - Skin microcirculation in middle-aged men with newly diagnosed arterial hypertension according to remote laser Doppler flowmetry data

T2 - Microvascular Research

AU - Fedorovich, Andrey A.

AU - Loktionova, Yulia I.

AU - Zharkikh, Elena V.

AU - Gorshkov, Alexander Y.

AU - Korolev, A.I.

AU - Dadaeva, Valida Arslanalievna

AU - Drapkina, Oxana M

AU - Zherebtsov, Evgeny A.

PY - 2022

DA - 2022/11/01 00:00:00

PB - Elsevier

SP - 104419

VL - 144

SN - 0026-2862

SN - 1095-9319

ER -

BibTex

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BibTex Copy

@article{2022_Fedorovich,

author = {Andrey A. Fedorovich and Yulia I. Loktionova and Elena V. Zharkikh and Alexander Y. Gorshkov and A.I. Korolev and Valida Arslanalievna Dadaeva and Oxana M Drapkina and Evgeny A. Zherebtsov},

title = {Skin microcirculation in middle-aged men with newly diagnosed arterial hypertension according to remote laser Doppler flowmetry data},

journal = {Microvascular Research},

year = {2022},

volume = {144},

publisher = {Elsevier},

month = {nov},

url = {https://doi.org/10.1016%2Fj.mvr.2022.104419},

pages = {104419},

doi = {10.1016/j.mvr.2022.104419}

}

Found error?

Publisher

Elsevier

Journal

Microvascular Research

Quartile SCImago

Quartile WOS

Impact factor

3.1

ISSN

00262862 (Print)
10959319 (Electronic)

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