Nanomedicine: Nanotechnology, Biology, and Medicine, volume 12, issue 6, pages 1663-1701
Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications
Kristof Zarschler
1
,
Louise Rocks
2
,
Nadia Licciardello
3, 4
,
L Boselli
2
,
Ester Polo
2
,
Karina Pombo García
1
,
Luisa De Cola
4
,
Holger Stephan
1
,
Kenneth H. Dawson
2
2
Centre For BioNano Interactions (CBNI), School of Chemistry and Chemical Biology, University College Dublin , Belfield, Dublin 4, Ireland.
|
Publication type: Journal Article
Publication date: 2016-08-01
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor: 5.4
ISSN: 15499634, 15499642
Medicine (miscellaneous)
Pharmaceutical Science
Molecular Medicine
General Materials Science
Bioengineering
Biomedical Engineering
Abstract
Ultrasmall nanoparticulate materials with core sizes in the 1-3nm range bridge the gap between single molecules and classical, larger-sized nanomaterials, not only in terms of spatial dimension, but also as regards physicochemical and pharmacokinetic properties. Due to these unique properties, ultrasmall nanoparticles appear to be promising materials for nanomedicinal applications. This review overviews the different synthetic methods of inorganic ultrasmall nanoparticles as well as their properties, characterization, surface modification and toxicity. We moreover summarize the current state of knowledge regarding pharmacokinetics, biodistribution and targeting of nanoscale materials. Aside from addressing the issue of biomolecular corona formation and elaborating on the interactions of ultrasmall nanoparticles with individual cells, we discuss the potential diagnostic, therapeutic and theranostic applications of ultrasmall nanoparticles in the emerging field of nanomedicine in the final part of this review.
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12
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Citations by publishers
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5
10
15
20
25
30
35
40
45
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American Chemical Society (ACS)
45 publications, 18.67%
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Royal Society of Chemistry (RSC)
44 publications, 18.26%
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Wiley
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Elsevier
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3 publications, 1.24%
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Hindawi Limited
3 publications, 1.24%
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2 publications, 0.83%
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Future Medicine
1 publication, 0.41%
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SAGE
1 publication, 0.41%
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Frontiers Media S.A.
1 publication, 0.41%
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King Saud University
1 publication, 0.41%
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Chinese Society of Rare Earths
1 publication, 0.41%
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Indian National Science Academy
1 publication, 0.41%
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Korean Society of Industrial Engineering Chemistry
1 publication, 0.41%
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Pleiades Publishing
1 publication, 0.41%
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SPIE
1 publication, 0.41%
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1 publication, 0.41%
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1 publication, 0.41%
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5
10
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20
25
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35
40
45
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Zarschler K. et al. Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications // Nanomedicine: Nanotechnology, Biology, and Medicine. 2016. Vol. 12. No. 6. pp. 1663-1701.
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Zarschler K., Rocks L., Licciardello N., Boselli L., Polo E., García K. P., De Cola L., Stephan H., Dawson K. H. Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications // Nanomedicine: Nanotechnology, Biology, and Medicine. 2016. Vol. 12. No. 6. pp. 1663-1701.
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TY - JOUR
DO - 10.1016/j.nano.2016.02.019
UR - https://linkinghub.elsevier.com/retrieve/pii/S1549963416300107
TI - Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications
T2 - Nanomedicine: Nanotechnology, Biology, and Medicine
AU - Zarschler, Kristof
AU - Rocks, Louise
AU - Licciardello, Nadia
AU - Boselli, L
AU - Polo, Ester
AU - García, Karina Pombo
AU - De Cola, Luisa
AU - Stephan, Holger
AU - Dawson, Kenneth H.
PY - 2016
DA - 2016/08/01 00:00:00
PB - Elsevier
SP - 1663-1701
IS - 6
VL - 12
SN - 1549-9634
SN - 1549-9642
ER -
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@article{2016_Zarschler,
author = {Kristof Zarschler and Louise Rocks and Nadia Licciardello and L Boselli and Ester Polo and Karina Pombo García and Luisa De Cola and Holger Stephan and Kenneth H. Dawson},
title = {Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications},
journal = {Nanomedicine: Nanotechnology, Biology, and Medicine},
year = {2016},
volume = {12},
publisher = {Elsevier},
month = {aug},
url = {https://linkinghub.elsevier.com/retrieve/pii/S1549963416300107},
number = {6},
pages = {1663--1701},
doi = {10.1016/j.nano.2016.02.019}
}
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Zarschler, Kristof, et al. “Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications.” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 12, no. 6, Aug. 2016, pp. 1663-1701. https://linkinghub.elsevier.com/retrieve/pii/S1549963416300107.