Nano Today, volume 11, issue 4, pages 435-463

Nanoparticles with multiple properties for biomedical applications: A strategic guide

Gabriel De Crozals 1
Romaric Bonnet 1
Carole Farre 1
Yves Chevalier 1
1
 
Univ Lyon, CNRS, Université Claude Bernard Lyon 1, ENS de Lyon, Institut des Sciences Analytiques, UMR 5280 5 rue de la Doua, F-69100, Villeurbanne, France.
Publication typeJournal Article
Publication date2016-08-01
Journal: Nano Today
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor17.4
ISSN17480132
Pharmaceutical Science
Biotechnology
General Materials Science
Bioengineering
Biomedical Engineering
Abstract
The technology to develop nanosized particles offering multiple properties carries tremendous potential for the development of applications in nanomedicine. Nanoparticles providing multimodal detection and/or multifunctionality could be of great interest in imaging applications, targeting, therapy and in vitro diagnostics. The precise control of surface chemistry is particularly important when nanomaterials are brought to interact with biology. Despite recent progress, the multifunctionalization of nanosized objects is still a major challenge for chemists. Here, we propose an overview of nanoparticle functionalization strategies, emphasizing those that permit the incorporation of multiple functions and/or biomolecules on the surface. This review is a general guide to help scientists to design nanoparticles tailored for specific biomedical applications. Multifunctional nanomaterials, ranging from core/shell structures to Janus nanoparticles, are explored and related chemistries are commented. The most promising and preferred materials are listed in relation to their applications and the main surface functionalization strategies are compared. New trends in multifunctionalization using solid-phase methods are also detailed.

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De Crozals G. et al. Nanoparticles with multiple properties for biomedical applications: A strategic guide // Nano Today. 2016. Vol. 11. No. 4. pp. 435-463.
GOST all authors (up to 50) Copy
De Crozals G., Bonnet R., Farre C., Chevalier Y. Nanoparticles with multiple properties for biomedical applications: A strategic guide // Nano Today. 2016. Vol. 11. No. 4. pp. 435-463.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.nantod.2016.07.002
UR - https://doi.org/10.1016/j.nantod.2016.07.002
TI - Nanoparticles with multiple properties for biomedical applications: A strategic guide
T2 - Nano Today
AU - De Crozals, Gabriel
AU - Bonnet, Romaric
AU - Farre, Carole
AU - Chevalier, Yves
PY - 2016
DA - 2016/08/01 00:00:00
PB - Elsevier
SP - 435-463
IS - 4
VL - 11
SN - 1748-0132
ER -
BibTex |
Cite this
BibTex Copy
@article{2016_De Crozals,
author = {Gabriel De Crozals and Romaric Bonnet and Carole Farre and Yves Chevalier},
title = {Nanoparticles with multiple properties for biomedical applications: A strategic guide},
journal = {Nano Today},
year = {2016},
volume = {11},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.nantod.2016.07.002},
number = {4},
pages = {435--463},
doi = {10.1016/j.nantod.2016.07.002}
}
MLA
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MLA Copy
De Crozals, Gabriel, et al. “Nanoparticles with multiple properties for biomedical applications: A strategic guide.” Nano Today, vol. 11, no. 4, Aug. 2016, pp. 435-463. https://doi.org/10.1016/j.nantod.2016.07.002.
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