Open Access

Pharmacological Research

, volume 156 , pages 104753

Gold Nanoparticles in Glioma Theranostics

Mohammad Norouzi ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Department of Pharmacology and Physiology, University of Montreal, Montreal, QC, Canada. |

Publication type: Journal Article

Publication date: 2020-06-01

Elsevier

Pharmacological Research

scimago Q1

wos Q1

SJR: 2.664

CiteScore: 18.6

Impact factor: 10.5

ISSN: 10436618, 10961186

DOI: 10.1016/j.phrs.2020.104753

Copy DOI

PubMed ID: 32209363

Pharmacology

Abstract

Despite many endeavors to treat malignant gliomas in the last decades, the median survival of patients has not significantly improved. The infiltrative nature of high-grade gliomas and the impermeability of the blood-brain barrier to the most therapeutic agents remain major hurdles, impeding an efficacious treatment. Theranostic platforms bridging diagnosis and therapeutic modalities aim to surmount the current limitations in diagnosis and therapy of glioma. Gold nanoparticles (AuNPs) due to their biocompatibility and tunable optical properties have widely been utilized for an assortment of theranostic purposes. In this Review, applications of AuNPs as imaging probes, drug/gene delivery systems, radiosensitizers, photothermal transducers, and multimodal theranostic agents in malignant gliomas are discussed. This Review also aims to provide a perspective on cancer theranostic applications of AuNPs in future clinical trials.

Found

1 citation

Mochalova Elizaveta

40 publications, 433 citations

h-index: 13

Moscow Institute of Physics and Technology

Research interests

Nanotechnology

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GOST Copy

Norouzi M. Gold Nanoparticles in Glioma Theranostics // Pharmacological Research. 2020. Vol. 156. p. 104753.

GOST all authors (up to 50) Copy

Norouzi M. Gold Nanoparticles in Glioma Theranostics // Pharmacological Research. 2020. Vol. 156. p. 104753.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.phrs.2020.104753

UR - https://doi.org/10.1016/j.phrs.2020.104753

TI - Gold Nanoparticles in Glioma Theranostics

T2 - Pharmacological Research

AU - Norouzi, Mohammad

PY - 2020

DA - 2020/06/01

PB - Elsevier

SP - 104753

VL - 156

PMID - 32209363

SN - 1043-6618

SN - 1096-1186

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2020_Norouzi,

author = {Mohammad Norouzi},

title = {Gold Nanoparticles in Glioma Theranostics},

journal = {Pharmacological Research},

year = {2020},

volume = {156},

publisher = {Elsevier},

month = {jun},

url = {https://doi.org/10.1016/j.phrs.2020.104753},

pages = {104753},

doi = {10.1016/j.phrs.2020.104753}

}

Publisher

Elsevier

Journal

Pharmacological Research

scimago Q1

wos Q1

SJR

2.664

CiteScore

18.6

Impact factor

10.5

ISSN

10436618 (Print)

10961186 (Electronic)