Progress in Polymer Science, volume 36, issue 8, pages 981-1014

Chitosan—A versatile semi-synthetic polymer in biomedical applications

Mamoni Dash ¹

Federica Chiellini ¹

R. M. Ottenbrite ²

E. Chiellini ¹

Hide authors affiliations Show authors affiliations: 2 affiliations

Laboratory of Bioactive Polymeric Materials for Biomedical and Environmental Applications (BIOlab), UdR INSTM, Department of Chemistry & Industrial Chemistry, University of Pisa, Pisa, Italy.

University of Pisa

National Interuniversity Consortium of Materials Science and Technology

Department of Chemistry, Virginia Commonwealth University, Richmond, VA, USA |

Publication type: Journal Article

Publication date: 2011-08-01

Elsevier

Journal: Progress in Polymer Science

Quartile SCImago

Quartile WOS

Impact factor: 27.1

ISSN: 00796700

DOI: 10.1016/j.progpolymsci.2011.02.001

Copy DOI

Materials Chemistry

Ceramics and Composites

Organic Chemistry

Polymers and Plastics

Surfaces and Interfaces

Abstract

This review outlines the new developments on chitosan-based bioapplications. Over the last decade, functional biomaterials research has developed new drug delivery systems and improved scaffolds for regenerative medicine that is currently one of the most rapidly growing fields in the life sciences. The aim is to restore or replace damaged body parts or lost organs by transplanting supportive scaffolds with appropriate cells that in combination with biomolecules generate new tissue. This is a highly interdisciplinary field that encompasses polymer synthesis and modification, cell culturing, gene therapy, stem cell research, therapeutic cloning and tissue engineering. In this regard, chitosan, as a biopolymer derived macromolecular compound, has a major involvement. Chitosan is a polyelectrolyte with reactive functional groups, gel-forming capability, high adsorption capacity and biodegradability. In addition, it is innately biocompatible and non-toxic to living tissues as well as having antibacterial, antifungal and antitumor activity. These features highlight the suitability and extensive applications that chitosan has in medicine. Micro/nanoparticles and hydrogels are widely used in the design of chitosan-based therapeuticsystems. The chemical structure and relevant biological properties of chitosan for regenerative medicine have been summarized as well as the methods for the preparation of controlled drug release devices and their applications.

By date By citations

Top-30

Citations by journals

	20 40 60 80 100 120 140
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 140, 6.41% International Journal of Biological Macromolecules 140 publications, 6.41%
Carbohydrate Polymers	Carbohydrate Polymers, 121, 5.54% Carbohydrate Polymers 121 publications, 5.54%
Polymers	Polymers, 39, 1.79% Polymers 39 publications, 1.79%
RSC Advances	RSC Advances, 34, 1.56% RSC Advances 34 publications, 1.56%
Materials Science and Engineering C	Materials Science and Engineering C, 33, 1.51% Materials Science and Engineering C 33 publications, 1.51%
Journal of Applied Polymer Science	Journal of Applied Polymer Science, 29, 1.33% Journal of Applied Polymer Science 29 publications, 1.33%
Molecules	Molecules, 26, 1.19% Molecules 26 publications, 1.19%
Journal of Materials Chemistry B	Journal of Materials Chemistry B, 25, 1.15% Journal of Materials Chemistry B 25 publications, 1.15%
Biomacromolecules	Biomacromolecules, 24, 1.1% Biomacromolecules 24 publications, 1.1%
Colloids and Surfaces B: Biointerfaces	Colloids and Surfaces B: Biointerfaces, 24, 1.1% Colloids and Surfaces B: Biointerfaces 24 publications, 1.1%
Materials	Materials, 21, 0.96% Materials 21 publications, 0.96%
International Journal of Pharmaceutics	International Journal of Pharmaceutics, 20, 0.92% International Journal of Pharmaceutics 20 publications, 0.92%
European Polymer Journal	European Polymer Journal, 19, 0.87% European Polymer Journal 19 publications, 0.87%
Acta Biomaterialia	Acta Biomaterialia, 19, 0.87% Acta Biomaterialia 19 publications, 0.87%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 18, 0.82% International Journal of Molecular Sciences 18 publications, 0.82%
Polymer Bulletin	Polymer Bulletin, 17, 0.78% Polymer Bulletin 17 publications, 0.78%
ACS applied materials & interfaces	ACS applied materials & interfaces, 17, 0.78% ACS applied materials & interfaces 17 publications, 0.78%
Pharmaceutics	Pharmaceutics, 15, 0.69% Pharmaceutics 15 publications, 0.69%
Marine Drugs	Marine Drugs, 15, 0.69% Marine Drugs 15 publications, 0.69%
International Journal of Polymeric Materials and Polymeric Biomaterials	International Journal of Polymeric Materials and Polymeric Biomaterials, 15, 0.69% International Journal of Polymeric Materials and Polymeric Biomaterials 15 publications, 0.69%
Reactive and Functional Polymers	Reactive and Functional Polymers, 14, 0.64% Reactive and Functional Polymers 14 publications, 0.64%
Journal of Biomedical Materials Research - Part A	Journal of Biomedical Materials Research - Part A, 14, 0.64% Journal of Biomedical Materials Research - Part A 14 publications, 0.64%
Journal of Drug Delivery Science and Technology	Journal of Drug Delivery Science and Technology, 12, 0.55% Journal of Drug Delivery Science and Technology 12 publications, 0.55%
Frontiers in Bioengineering and Biotechnology	Frontiers in Bioengineering and Biotechnology, 11, 0.5% Frontiers in Bioengineering and Biotechnology 11 publications, 0.5%
Scientific Reports	Scientific Reports, 11, 0.5% Scientific Reports 11 publications, 0.5%
Journal of Molecular Liquids	Journal of Molecular Liquids, 11, 0.5% Journal of Molecular Liquids 11 publications, 0.5%
Journal of Biomaterials Science, Polymer Edition	Journal of Biomaterials Science, Polymer Edition, 11, 0.5% Journal of Biomaterials Science, Polymer Edition 11 publications, 0.5%
Langmuir	Langmuir, 10, 0.46% Langmuir 10 publications, 0.46%
Nanomaterials	Nanomaterials, 10, 0.46% Nanomaterials 10 publications, 0.46%
	20 40 60 80 100 120 140

Citations by publishers

	100 200 300 400 500 600 700 800
Elsevier	Elsevier, 787, 36.05% Elsevier 787 publications, 36.05%
Wiley	Wiley, 226, 10.35% Wiley 226 publications, 10.35%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 206, 9.44% Multidisciplinary Digital Publishing Institute (MDPI) 206 publications, 9.44%
Springer Nature	Springer Nature, 197, 9.02% Springer Nature 197 publications, 9.02%
American Chemical Society (ACS)	American Chemical Society (ACS), 113, 5.18% American Chemical Society (ACS) 113 publications, 5.18%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 112, 5.13% Royal Society of Chemistry (RSC) 112 publications, 5.13%
Taylor & Francis	Taylor & Francis, 91, 4.17% Taylor & Francis 91 publications, 4.17%
IOP Publishing	IOP Publishing, 23, 1.05% IOP Publishing 23 publications, 1.05%
SAGE	SAGE, 20, 0.92% SAGE 20 publications, 0.92%
Trans Tech Publications	Trans Tech Publications, 20, 0.92% Trans Tech Publications 20 publications, 0.92%
Frontiers Media S.A.	Frontiers Media S.A., 18, 0.82% Frontiers Media S.A. 18 publications, 0.82%
Pleiades Publishing	Pleiades Publishing, 15, 0.69% Pleiades Publishing 15 publications, 0.69%
Hindawi Limited	Hindawi Limited, 14, 0.64% Hindawi Limited 14 publications, 0.64%
American Institute of Physics (AIP)	American Institute of Physics (AIP), 11, 0.5% American Institute of Physics (AIP) 11 publications, 0.5%
Bentham Science	Bentham Science, 10, 0.46% Bentham Science 10 publications, 0.46%
The Korean Fiber Society	The Korean Fiber Society, 8, 0.37% The Korean Fiber Society 8 publications, 0.37%
Future Medicine	Future Medicine, 7, 0.32% Future Medicine 7 publications, 0.32%
Walter de Gruyter	Walter de Gruyter, 6, 0.27% Walter de Gruyter 6 publications, 0.27%
Cambridge University Press	Cambridge University Press, 6, 0.27% Cambridge University Press 6 publications, 0.27%
King Saud University	King Saud University, 5, 0.23% King Saud University 5 publications, 0.23%
Public Library of Science (PLoS)	Public Library of Science (PLoS), 5, 0.23% Public Library of Science (PLoS) 5 publications, 0.23%
Wolters Kluwer Health	Wolters Kluwer Health, 4, 0.18% Wolters Kluwer Health 4 publications, 0.18%
American Vacuum Society	American Vacuum Society, 4, 0.18% American Vacuum Society 4 publications, 0.18%
World Scientific	World Scientific, 4, 0.18% World Scientific 4 publications, 0.18%
Institution of Engineering and Technology (IET)	Institution of Engineering and Technology (IET), 3, 0.14% Institution of Engineering and Technology (IET) 3 publications, 0.14%
KeAi Communications Co.	KeAi Communications Co., 3, 0.14% KeAi Communications Co. 3 publications, 0.14%
Scientific Research Publishing	Scientific Research Publishing, 3, 0.14% Scientific Research Publishing 3 publications, 0.14%
Beilstein-Institut	Beilstein-Institut, 2, 0.09% Beilstein-Institut 2 publications, 0.09%
The Royal Society	The Royal Society, 2, 0.09% The Royal Society 2 publications, 0.09%
	100 200 300 400 500 600 700 800

We do not take into account publications without a DOI.
Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
Statistics recalculated weekly.

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GOST Copy

Dash M. et al. Chitosan—A versatile semi-synthetic polymer in biomedical applications // Progress in Polymer Science. 2011. Vol. 36. No. 8. pp. 981-1014.

GOST all authors (up to 50) Copy

Dash M., Chiellini F., Ottenbrite R. M., Chiellini E. Chitosan—A versatile semi-synthetic polymer in biomedical applications // Progress in Polymer Science. 2011. Vol. 36. No. 8. pp. 981-1014.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.progpolymsci.2011.02.001

UR - https://doi.org/10.1016/j.progpolymsci.2011.02.001

TI - Chitosan—A versatile semi-synthetic polymer in biomedical applications

T2 - Progress in Polymer Science

AU - Dash, Mamoni

AU - Chiellini, Federica

AU - Ottenbrite, R. M.

AU - Chiellini, E.

PY - 2011

DA - 2011/08/01 00:00:00

PB - Elsevier

SP - 981-1014

IS - 8

VL - 36

SN - 0079-6700

ER -

BibTex |

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BibTex Copy

@article{2011_Dash,

author = {Mamoni Dash and Federica Chiellini and R. M. Ottenbrite and E. Chiellini},

title = {Chitosan—A versatile semi-synthetic polymer in biomedical applications},

journal = {Progress in Polymer Science},

year = {2011},

volume = {36},

publisher = {Elsevier},

month = {aug},

url = {https://doi.org/10.1016/j.progpolymsci.2011.02.001},

number = {8},

pages = {981--1014},

doi = {10.1016/j.progpolymsci.2011.02.001}

}

MLA

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MLA Copy

Dash, Mamoni, et al. “Chitosan—A versatile semi-synthetic polymer in biomedical applications.” Progress in Polymer Science, vol. 36, no. 8, Aug. 2011, pp. 981-1014. https://doi.org/10.1016/j.progpolymsci.2011.02.001.

Found error?

Publisher

Elsevier

Journal

Progress in Polymer Science

Quartile SCImago

Quartile WOS

Impact factor

27.1

ISSN

00796700 (Print)