Highly selective on-off fluorescence recognition of Fe3+ based on a coumarin derivative and its application in live-cell imaging

Publication typeJournal Article
Publication date2018-01-01
scimago Q2
wos Q1
SJR0.664
CiteScore8.5
Impact factor4.6
ISSN13861425, 18733557
Spectroscopy
Analytical Chemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Abstract
A novel coumarin chemosensor, 7-hydroxy-2-oxo-N-(pyridin-2-ylmethyl)chromene-3-carboxamide (Probe 1), demonstrated significant selectivity towards Fe3+ ions. Probe 1 exhibited high fluorescence emission profile at 447nm, excellent selectivity towards Fe3+ over other biologically important metal ions (Al3+, Ba2+, Co2+, Cu2+, Zn2+, Cd2+, Hg2+, Pb2+ and Sn2+). Interestingly, there was ~30-fold decrease in fluorescence intensity upon Fe3+ binding. The limit of detection of Fe3+ was found to be 0.76μM (~40ppb). Probe 1 also exhibited high potential as an intracellular chemosensor for Fe3+.
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Warrier S., Kharkar P. S. Highly selective on-off fluorescence recognition of Fe3+ based on a coumarin derivative and its application in live-cell imaging // Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 2018. Vol. 188. pp. 659-665.
GOST all authors (up to 50) Copy
Warrier S., Kharkar P. S. Highly selective on-off fluorescence recognition of Fe3+ based on a coumarin derivative and its application in live-cell imaging // Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 2018. Vol. 188. pp. 659-665.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.saa.2017.07.068
UR - https://doi.org/10.1016/j.saa.2017.07.068
TI - Highly selective on-off fluorescence recognition of Fe3+ based on a coumarin derivative and its application in live-cell imaging
T2 - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
AU - Warrier, Sona
AU - Kharkar, Prashant S.
PY - 2018
DA - 2018/01/01
PB - Elsevier
SP - 659-665
VL - 188
PMID - 28803123
SN - 1386-1425
SN - 1873-3557
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Warrier,
author = {Sona Warrier and Prashant S. Kharkar},
title = {Highly selective on-off fluorescence recognition of Fe3+ based on a coumarin derivative and its application in live-cell imaging},
journal = {Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy},
year = {2018},
volume = {188},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.saa.2017.07.068},
pages = {659--665},
doi = {10.1016/j.saa.2017.07.068}
}