Open Access
Open access
Elsevier
Stem Cell Research
,  volume 48 ,  pages 101933

Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation

Ekaterina Kondrateva 1
, 
Elmira P Adilgereeva 1
, 
Elena A Amelina 2
, 
Vyacheslav Tabakov 1
, 
A Demchenko 1
, 
K Ustinov 1
, 
Matvey Yasinovsky 1
, 
Ekaterina Voronina 1
, 
A. V. Lavrov 1
, 
S. A. Smirnikhina 1
1
 
2
 
Publication type: Journal Article
Publication date: 2020-10-01
Elsevier
scimago Q3
wos Q4
SJR: 0.495
CiteScore: 1.8
Impact factor: 0.7
ISSN: 18735061, 18767753
General Medicine
Cell Biology
Developmental Biology
Abstract
Skin fibroblasts obtained from a 27-year-old man with clinically manifested and genetically proven (F508del/F508del) cystic fibrosis were successfully transformed into induced pluripotent stem cells (iPSCs) by using Sendai virus-based reprogramming vectors including the four Yamanaka factors, OCT3/4, SOX2, KLF4, and c-MYC. The iPSCs showed a normal karyotype, expressed pluripotency markers and exhibited the potential to differentiate into three germ layers in spontaneous differentiation assay. This iPSC line may be subsequently used for development of a personalized etiotropic treatment including genome editing, and for disease modelling and drug screening.
Found 
Found 

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GOST Copy
Kondrateva E. et al. Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation // Stem Cell Research. 2020. Vol. 48. p. 101933.
GOST all authors (up to 50) Copy
Kondrateva E., Adilgereeva E. P., Amelina E. A., Tabakov V., Demchenko A., Ustinov K., Yasinovsky M., Voronina E., Lavrov A. V., Smirnikhina S. A. Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation // Stem Cell Research. 2020. Vol. 48. p. 101933.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.scr.2020.101933
UR - https://doi.org/10.1016/j.scr.2020.101933
TI - Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation
T2 - Stem Cell Research
AU - Kondrateva, Ekaterina
AU - Adilgereeva, Elmira P
AU - Amelina, Elena A
AU - Tabakov, Vyacheslav
AU - Demchenko, A
AU - Ustinov, K
AU - Yasinovsky, Matvey
AU - Voronina, Ekaterina
AU - Lavrov, A. V.
AU - Smirnikhina, S. A.
PY - 2020
DA - 2020/10/01
PB - Elsevier
SP - 101933
VL - 48
PMID - 32777768
SN - 1873-5061
SN - 1876-7753
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Kondrateva,
author = {Ekaterina Kondrateva and Elmira P Adilgereeva and Elena A Amelina and Vyacheslav Tabakov and A Demchenko and K Ustinov and Matvey Yasinovsky and Ekaterina Voronina and A. V. Lavrov and S. A. Smirnikhina},
title = {Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation},
journal = {Stem Cell Research},
year = {2020},
volume = {48},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/j.scr.2020.101933},
pages = {101933},
doi = {10.1016/j.scr.2020.101933}
}