Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene
Lara Bianchi
1
,
Massimo Maccagno
1
,
G. Petrillo
1
,
Egon Rizzato
2
,
Fernando Sancassan
1
,
Donatella Spinelli
3
,
Cinzia Tavani
1
Publication type: Journal Article
Publication date: 2011-10-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
The base-induced cyclization of ( E )-2-aryl-1-[2-(benzylsulfonyl)phenyl]-1-nitroethenes to polysubstituted thiochroman S , S -dioxides exhibits a diastereoselectivity that can be oriented towards a selected isomer by means of appropriate adjustments of the experimental conditions. The interest of such a result also rests on the promising pharmacological activity of the products, whose structure encompasses different well-acknowledged pharmacophores. A conformational 1 H NMR investigation, backed by molecular-mechanics calculations, has also been accomplished.
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15
Total citations:
15
Citations from 2025:
1
(6.67%)
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GOST
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Bianchi L. et al. Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene // Tetrahedron. 2011. Vol. 67. No. 42. pp. 8160-8169.
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Bianchi L., Maccagno M., Petrillo G., Rizzato E., Sancassan F., Spinelli D., Tavani C. Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene // Tetrahedron. 2011. Vol. 67. No. 42. pp. 8160-8169.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.tet.2011.08.038
UR - https://doi.org/10.1016/j.tet.2011.08.038
TI - Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene
T2 - Tetrahedron
AU - Bianchi, Lara
AU - Maccagno, Massimo
AU - Petrillo, G.
AU - Rizzato, Egon
AU - Sancassan, Fernando
AU - Spinelli, Donatella
AU - Tavani, Cinzia
PY - 2011
DA - 2011/10/01
PB - Elsevier
SP - 8160-8169
IS - 42
VL - 67
SN - 0040-4020
SN - 1464-5416
ER -
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BibTex (up to 50 authors)
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@article{2011_Bianchi,
author = {Lara Bianchi and Massimo Maccagno and G. Petrillo and Egon Rizzato and Fernando Sancassan and Donatella Spinelli and Cinzia Tavani},
title = {Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene},
journal = {Tetrahedron},
year = {2011},
volume = {67},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/j.tet.2011.08.038},
number = {42},
pages = {8160--8169},
doi = {10.1016/j.tet.2011.08.038}
}
Cite this
MLA
Copy
Bianchi, Lara, et al. “Access to 2,3-diaryl-4-nitrothiochroman S,S-dioxides from 3-nitrobenzo[b]thiophene.” Tetrahedron, vol. 67, no. 42, Oct. 2011, pp. 8160-8169. https://doi.org/10.1016/j.tet.2011.08.038.