An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides
Тип публикации: Journal Article
Дата публикации: 2012-03-01
scimago Q3
wos Q2
БС2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Краткое описание
An efficient approach of highly stereoselective synthesis of novel trifluoromethylated trans-4,5-dihydrofuro[2,3-c]pyrazoles has been described. Arsonium bromides 1 reacted smoothly with the electron-deficient alkenes (Z)-4-aryl-1-phenyl-3-(trifluoromethyl)-1H-pyrozol-5(4H)-ones 2 to give products trans-dihydrofuro[2,3-c]pyrazoles 3 with high stereoselectivity and in good to excellent yields, using CH2Cl2 as solvent and K2CO3 as base.
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Zhang J. et al. An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides // Tetrahedron. 2012. Vol. 68. No. 9. pp. 2121-2127.
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Zhang J., Yang S., Zhang K., Chen J., Deng H., Shao M., Zhang H., Cao W. An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides // Tetrahedron. 2012. Vol. 68. No. 9. pp. 2121-2127.
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TY - JOUR
DO - 10.1016/j.tet.2012.01.030
UR - https://doi.org/10.1016/j.tet.2012.01.030
TI - An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides
T2 - Tetrahedron
AU - Zhang, Jiaping
AU - Yang, Shuxin
AU - Zhang, Kai
AU - Chen, Jie
AU - Deng, Hongmei
AU - Shao, Min
AU - Zhang, Hui
AU - Cao, Weiguo
PY - 2012
DA - 2012/03/01
PB - Elsevier
SP - 2121-2127
IS - 9
VL - 68
SN - 0040-4020
SN - 1464-5416
ER -
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@article{2012_Zhang,
author = {Jiaping Zhang and Shuxin Yang and Kai Zhang and Jie Chen and Hongmei Deng and Min Shao and Hui Zhang and Weiguo Cao},
title = {An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides},
journal = {Tetrahedron},
year = {2012},
volume = {68},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.tet.2012.01.030},
number = {9},
pages = {2121--2127},
doi = {10.1016/j.tet.2012.01.030}
}
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MLA
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Zhang, Jiaping, et al. “An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides.” Tetrahedron, vol. 68, no. 9, Mar. 2012, pp. 2121-2127. https://doi.org/10.1016/j.tet.2012.01.030.