ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins
Publication type: Journal Article
Publication date: 2012-07-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A new protocol for the synthesis of polysubstituted isocoumarins from 2-iodobenzoic acid and β-diketone compounds has been developed. The occurrence of C-arylation cyclization reaction in transition-metal-free systems and ortho-induced substrates has been exploited. Reactions using these inexpensive conditions have displayed high functional group tolerance and excellent yields.
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32
Total citations:
32
Citations from 2024:
4
(12.51%)
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GOST
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Liu L. et al. ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins // Tetrahedron. 2012. Vol. 68. No. 27-28. pp. 5391-5395.
GOST all authors (up to 50)
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Liu L., Hu J., Wang X., Zhong M. J., Liu X., Yang S. D., Liang Y. ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins // Tetrahedron. 2012. Vol. 68. No. 27-28. pp. 5391-5395.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.tet.2012.04.111
UR - https://doi.org/10.1016/j.tet.2012.04.111
TI - ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins
T2 - Tetrahedron
AU - Liu, Lei
AU - Hu, Jie
AU - Wang, Xiangchuan
AU - Zhong, Mei Jin
AU - Liu, Xue-Yuan
AU - Yang, Shang Dong
AU - Liang, Yong-Min
PY - 2012
DA - 2012/07/01
PB - Elsevier
SP - 5391-5395
IS - 27-28
VL - 68
SN - 0040-4020
SN - 1464-5416
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2012_Liu,
author = {Lei Liu and Jie Hu and Xiangchuan Wang and Mei Jin Zhong and Xue-Yuan Liu and Shang Dong Yang and Yong-Min Liang},
title = {ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins},
journal = {Tetrahedron},
year = {2012},
volume = {68},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.tet.2012.04.111},
number = {27-28},
pages = {5391--5395},
doi = {10.1016/j.tet.2012.04.111}
}
Cite this
MLA
Copy
Liu, Lei, et al. “ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins.” Tetrahedron, vol. 68, no. 27-28, Jul. 2012, pp. 5391-5395. https://doi.org/10.1016/j.tet.2012.04.111.