Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane
B. A. Trofimov
1
,
Al'bina I Mikhaleva
1
,
Andrei V. Ivanov
1
,
Viktoria S Shcherbakova
1
,
Igor Ushakov
1
Publication type: Journal Article
Publication date: 2015-01-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
2- and 2,3-Substituted pyrroles are readily synthesized in a one-pot procedure from ketones, hydroxylamine hydrochloride, and 1,2-dichloroethane in the KOH/DMSO system (120 °C, 2–4 h), the yields of pyrroles ranging 11–85%. Aliphatic, cycloaliphatic, aromatic, and heteroaromatic ketones tolerate the reaction conditions.
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Total citations:
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Citations from 2025:
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(7.69%)
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GOST
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Trofimov B. A. et al. Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane // Tetrahedron. 2015. Vol. 71. No. 1. pp. 124-128.
GOST all authors (up to 50)
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Trofimov B. A., Mikhaleva A. I., Ivanov A. V., Shcherbakova V. S., Ushakov I. Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane // Tetrahedron. 2015. Vol. 71. No. 1. pp. 124-128.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.tet.2014.11.031
UR - https://doi.org/10.1016/j.tet.2014.11.031
TI - Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane
T2 - Tetrahedron
AU - Trofimov, B. A.
AU - Mikhaleva, Al'bina I
AU - Ivanov, Andrei V.
AU - Shcherbakova, Viktoria S
AU - Ushakov, Igor
PY - 2015
DA - 2015/01/01
PB - Elsevier
SP - 124-128
IS - 1
VL - 71
SN - 0040-4020
SN - 1464-5416
ER -
Cite this
BibTex (up to 50 authors)
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@article{2015_Trofimov,
author = {B. A. Trofimov and Al'bina I Mikhaleva and Andrei V. Ivanov and Viktoria S Shcherbakova and Igor Ushakov},
title = {Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane},
journal = {Tetrahedron},
year = {2015},
volume = {71},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.tet.2014.11.031},
number = {1},
pages = {124--128},
doi = {10.1016/j.tet.2014.11.031}
}
Cite this
MLA
Copy
Trofimov, B. A., et al. “Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane.” Tetrahedron, vol. 71, no. 1, Jan. 2015, pp. 124-128. https://doi.org/10.1016/j.tet.2014.11.031.
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